TRANS-1-CINNAMYLPIPERAZINE Chemical Properties

Melting point:

39-44 °C(lit.)

Boiling point:

129 °C1 mm Hg(lit.)

Density 

0.989 g/mL at 25 °C(lit.)

refractive index 

1.574-1.576

Flash point:

>230 °F

pka

9.17±0.10(Predicted)

Specific Gravity

0.989

CAS DataBase Reference

18903-01-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29335995

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

TRANS-1-CINNAMYLPIPERAZINE Usage And Synthesis

Description

trans-1-Cinnamylpiperazine is a piperazine derivative. It was used as a test compound to investigate the in vitro efficacy as an antiprotozoal against Philasterides dicentrarchi. It may be used to synthesize Incentrom A derivatives.

Chemical Properties

clear colorless to yellow liquid after melting

Uses

1-Cinnamylpiperazine is a useful building block and a metabolite of Flunarizine (F455200), which is a selective calcium entry blocker used for prophylaxis of severe refractory migraine and symptomatic treatment of vestibular vertigo.

TRANS-1-CINNAMYLPIPERAZINE(18903-01-0)Related Product Information

• TRANS-1-CINNAMYLPIPERAZINE
• Stugeron
• Flunarizine
• Cinepazic Acid
• Flunarizine dihydrochloride
• trans-1-Cinnamylpiperazine
• CINNAMYL PIEPRAZINE HYDROCHLORIDE
• 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE
• 1-(2-(BIS-(4-FLUOROPHENYL)METHOXY)ETHYL)-4-(3-PHENYL-2-PROPENYL)PIPERAZINE DIHYDROCHLORIDE
• Lorcinadol
• 4-(3-PHENYLPROP-2-ENYL)-1-(PHENYLSULFONYL)PIPERAZINE
• 1-(4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)HEXAN-1-ONE
• 1-(4-BROMOPHENYL)-3-[4-(3-PHENYL-2-PROPENYL)PIPERAZINO]DIHYDRO-1H-PYRROLE-2,5-DIONE
• (E)-3-(4-CINNAMYLPIPERAZIN-1-YL)-1-(4-FLUOROPHENYL)PYRROLIDINE-2,5-DIONE
• 3,5-DINITROPHENYL 4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL KETONE
• 4-CHLORO-1-((4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)SULFONYL)BENZENE
• 2-((4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)CARBONYL)CYCLOHEXANECARBOXYLIC ACID
• N-(4-CHLOROPHENYL)(4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)FORMAMIDE