Crotonic anhydride Chemical Properties

Melting point:

-20°C

Boiling point:

248 °C(lit.)

Density 

1.04 g/mL at 25 °C(lit.)

vapor pressure 

1 hPa (25 °C)

refractive index 

n20/D 1.473(lit.)

Flash point:

231 °F

storage temp. 

Store below +30°C.

solubility 

soluble in Ether

form 

clear liquid

color 

Colorless to Light orange to Yellow

CAS DataBase Reference

623-68-7(CAS DataBase Reference)

EPA Substance Registry System

2-Butenoic acid, anhydride (623-68-7)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8/PG 3

WGK Germany 

3

RTECS 

GQ6125000

Autoignition Temperature

290 °C

HS Code 

2916 19 95

HazardClass 

8

PackingGroup 

III

Hazardous Substances Data

623-68-7(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 2061 mg/kg

MSDS

• Language:English Provider:SigmaAldrich

Crotonic anhydride Usage And Synthesis

Uses

Crotonic anhydride belongs to the organic chemical intermediates, is an important organic chemical raw materials, in the dyestuff industry is used as fur dyes, reactive dyestuffs intermediates; in the cosmetic industry is used as a high-grade cosmetics, such as skin creams, hair conditioners, shampoos, creams, and other additives; in the pharmaceutical industry as a pharmaceutical antimicrobial drugs, sulfonamides as raw materials for drugs. Crotonic anhydride can also be used in the preparation of butenoic acid fiber and coal dye, hair dye, color developer, epoxy resin curing agent, petroleum additives, rubber antioxidants and other synthetic.

Chemical Properties

Colorless to pale yellow liquid

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 593, 1992 DOI: 10.1016/S0040-4039(00)92318-9

Safety Profile

Moderately toxic by ingestion. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Crotonic anhydride(623-68-7)Related Product Information

• Phthalic anhydride
• CIS-BUTENEDIOIC ANHYDRIDE
• Trifluoromethanesulfonic anhydride
• Chromium(VI) oxide
• Trimellitic Anhydride
• Di-tert-butyl dicarbonate
• Succinic anhydride
• Isatoic Anhydride
• Erythromycin Estolate
• Acetic anhydride
• 3-PHENYLACRYLIC ANHYDRIDE
• CROTONIC ANHYDRIDE, 95%, PREDOMINANTLY T RANS
• Crotonic acid
• ABERCHROME 670
• TIGLIC ANHYDRIDE
• Crotonic anhydride
• 3,4,5-TRIMETHOXYCINNAMIC ACID ANHYDRIDE
• TOSLAB 97311