Cyanoacetohydrazide Chemical Properties

Melting point:

108-110 °C (lit.)

Boiling point:

185.55°C (rough estimate)

Density 

1.3131 (rough estimate)

refractive index 

1.4500 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO : 150 mg/mL (1513.78 mM)

form 

powder to crystal

pka

pK1:2.34(+2);pK2:11.17(+1) (25°C)

color 

White to Light yellow to Light orange

Water Solubility 

almost transparency

Merck 

14,2680

BRN 

1751498

CAS DataBase Reference

140-87-4(CAS DataBase Reference)

NIST Chemistry Reference

Alpha-cyanoacetic acid, hydrazide(140-87-4)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-28-36/37/39-45

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

AG4200000

Hazard Note 

Irritant

HazardClass 

6.1

PackingGroup 

III

HS Code 

29280090

Hazardous Substances Data

140-87-4(Hazardous Substances Data)

Toxicity

mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,

MSDS

• Language:English Provider:Cyacetacide
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Cyanoacetohydrazide Usage And Synthesis

Chemical Properties

BROWN GRANULAR CRYSTALLINE POWDER

Uses

2-Cyanoacetohydrazide is used in the study of the viral inhibiting activity of some potential antiviral agents.

Purification Methods

Crystallise the hydrazide from EtOH. The hydrochloride has m 178-180o and the benzylidene derivative has m 178o. It is converted to 3-oxo-5-iminopyrazolidine in hot 40% aqueous NaOH. [Beilstein 2 H 591, 2 I 256, 2 III 1636.] IRRITANT.

Cyanoacetohydrazide(140-87-4)Related Product Information

• Citric acid
• ETHYL 2-CYANOACRYLATE
• Sodium cyanoborohydride
• Acetylacetone
• Ethyl 2-(Chlorosulfonyl)acetate
• 2-Cyanoacetamide
• Acetylcholine
• Acetylspiramycin
• Acetaminophen
• Maleic hydrazide
• Methylene dithiocyanate
• Ethyl isocyanoacetate
• Acethydrazide
• Ethyl cyanoacetate
• Acetylsalicylic acid
• Folic acid
• Ethyl cyanoformate
• Cyanoacetic acid