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3-Bromo-2-pyridinamine

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3-Bromo-2-pyridinamine Basic information

Product Name:
3-Bromo-2-pyridinamine
Synonyms:
  • 3-BROMO-2-PYRIDINAMINE
  • 3-BROMOPYRIDIN-2-AMINE
  • 3-BROMO-PYRIDIN-2-YLAMINE
  • 2-AMINO-3-BROMOPYRIDINE
  • IFLAB-BB F1371-0194
  • 2-Pyridinamine, 3-bromo-
  • TIMTEC-BB SBB005538
  • 2-AMINO-3-BROMOPYRIDINE 97%
CAS:
13534-99-1
MF:
C5H5BrN2
MW:
173.01
EINECS:
629-620-5
Product Categories:
  • Boronic Acid
  • C5Heterocyclic Building Blocks
  • Pyridine
  • pharmacetical
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridine series
  • Pyridines
Mol File:
13534-99-1.mol
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3-Bromo-2-pyridinamine Chemical Properties

Melting point:
63-67 °C
Boiling point:
232.0±20.0 °C(Predicted)
Density 
1.6065 (rough estimate)
vapor pressure 
0.83-1.8Pa at 20-25℃
refractive index 
1.5182 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Powder
pka
4.14±0.36(Predicted)
color 
Gray to brown
BRN 
109867
LogP
1.5 at 20℃ and pH7
CAS DataBase Reference
13534-99-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
PackingGroup 
II
HS Code 
29333990

MSDS

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3-Bromo-2-pyridinamine Usage And Synthesis

Chemical Properties

grey to brown powder

Uses

2-Amino-3-bromopyridine may be used to synthesize:

  • 2-acylamido-3-bromopyridines
  • 2-anilino-3-bromopyridine
  • 3-[(2-methoxyphenyl)ethynyl]pyridin-2-amine
  • 3-[(4-methoxyphenyl)ethynyl]pyridin-2-amine
  • N-(bromopyridyl)amidines
  • carbolines via palladium catalyzed arylation followed by palladium catalyzed amination reaction
  • 2-amino-3-cyanopyridine via palladium catalyzed cyanation reaction with potassium ferro-cyanide in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene [DBU]
  • nitro-substituted N,N′-dipyridinylamines via palladium catalyzed coupling reaction with 2-chloro-3-nitropyridine in the presence of Xantphos ligand
  • 2-amino-3-iodopyridine via reaction with sodium iodide in the presence of copper(I)iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine

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