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2,6-Dichlorobenzyl bromide

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2,6-Dichlorobenzyl bromide Basic information

Product Name:
2,6-Dichlorobenzyl bromide
Synonyms:
  • alpha-Bromo-2,6-dichlorotoluene, 2-(Bromomethyl)-1,3-dichlorobenzene
  • 2,6-two chlorobenzyl broMide
  • A-BROMO-2,6-DICHLOROTOLUENE
  • ALPHA-BROMO-2,6-DICHLOROTOLUENE
  • 2-(BROMOMETHYL)-1,3-DICHLOROBENZENE
  • 2,6-DICHLOROBENZYL BROMIDE
  • 1-BROMOMETHYL-2,6-DICHLOROBENZENE
  • DICHLOROBENZYL(2,6-) BROMIDE
CAS:
20443-98-5
MF:
C7H5BrCl2
MW:
239.92
EINECS:
243-827-4
Mol File:
20443-98-5.mol
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2,6-Dichlorobenzyl bromide Chemical Properties

Melting point:
54-56 °C(lit.)
Boiling point:
>110°C
Density 
1.5832 (rough estimate)
refractive index 
1.5700 (estimate)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
methanol: 0.1 g/mL, clear
form 
Crystals or Crystalline Powder
color 
Colorless to white
BRN 
637351
CAS DataBase Reference
20443-98-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 2-(bromomethyl)-1,3-dichloro-(20443-98-5)
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Safety Information

Hazard Codes 
C
Risk Statements 
34-36/37-36
Safety Statements 
22-26-27-28-36/37/39-45-25
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
XS7966000
19
HazardClass 
8
PackingGroup 
II
HS Code 
29039990

MSDS

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2,6-Dichlorobenzyl bromide Usage And Synthesis

Chemical Properties

White solid

Uses

2,6-Dichlorobenzyl Bromide is used in the preparation of potent epoxide hydrolase inhibitors. Has shown thus far to relieve hypotension in lipopolysaccharide deficient murine models. As well they have been used in the synthesis of anti-HIV drugs based on diaryltriazine (DATA) analogues.

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 707, 1988 DOI: 10.1016/S0040-4039(00)80190-2

2,6-Dichlorobenzyl bromide Preparation Products And Raw materials

Preparation Products

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