1,8-Octanediol Chemical Properties

Melting point:

57-61 °C (lit.)

Boiling point:

172 °C/20 mmHg (lit.)

Density 

1,053g/cm

refractive index 

1,438-1,44

Flash point:

148°C

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Powder or Crystalline

pka

14.89±0.10(Predicted)

color 

Off-white to pale yellow

Water Solubility 

Soluble in water and methanol.

BRN 

1633499

InChI

InChI=1S/C8H18O2/c9-7-5-3-1-2-4-6-8-10/h9-10H,1-8H2

InChIKey

OEIJHBUUFURJLI-UHFFFAOYSA-N

SMILES

C(O)CCCCCCCO

LogP

0.970 (est)

CAS DataBase Reference

629-41-4(CAS DataBase Reference)

NIST Chemistry Reference

1,8-Octanediol(629-41-4)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-37/39-24/25

WGK Germany 

3

HS Code 

29053980

MSDS

• Language:English Provider:Octane-1,8-diol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,8-Octanediol Usage And Synthesis

Chemical Properties

colorless to white crystals or flakes. soluble in ethanol, insoluble in water, ether, light gasoline.

Uses

As a monomer, 1,8-Octanediol is used in the synthesis of polymers polyesters and polyurethane.

Application

1,8-Octanediol is used in cosmetics, perfumes, ink, essence and in UV coating. It acts as a precursor in the synthesis of polymer and in the manufacture of pharmaceuticals. 1,8-Octanediol can undergo:
Polycondensation with citric acid to form biodegradable poly(1,8-octanediol citrate)(POC) crosslinked bioelastomer which can be blended with various additives.
Fischer esterification with dicarboxylic acids to form diol-based macromers.

Preparation

1,8-Octanediol is synthesized by hydrogenation reduction under high temperature and high pressure using diethyl suberate as raw material and copper-chromium oxide as catalyst.

Definition

ChEBI: Octane-1,8-diol is an octanediol.

Purification Methods

Recrystallise the diol from EtOH and distil it in a vacuum. [Beilstein 1 IV 2592.]

1,8-Octanediol(629-41-4)Related Product Information

• 4,4'-BICYCLOHEXANOL
• Dimethyl suberate
• Hyodeoxycholic acid
• 1,2,7,8-DIEPOXYOCTANE
• fluocinolone16,17-acetonide
• Hydrocortisone
• G-STROPHANTHIN
• Dibutyl suberate
• trans-1,2-Cyclohexanedicarboxylic acid
• Triamcinolone
• Prednisolone
• SUBERIC ACID MONOMETHYL ESTER
• Suberic acid
• HECOGENIN ACETATE
• CORTICOSTERONE 21-ACETATE
• DIGOXIN
• DIETHYL SUBERATE
• 1,8-Octanediol