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4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid hemisodium salt

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4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid hemisodium salt Basic information

Product Name:
4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid hemisodium salt
Synonyms:
  • HEPES NA-SALT
  • HEPES, SODIUM
  • 2-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]ETHANESULFONIC ACID SODIUM SALT
  • 4-(2-HYDROXYETHYL)-1-PIPERAZINEETHANESULFONIC ACID, DISODIUM SALT
  • 4-(2-HYDROXYETHYL)-1-PIPERAZINEETHANE-SULFONIC ACID HALF-SODIUM SALT
  • 4-(2-HYDROXYETHYL)-1-PIPERAZINEETHANESULFONIC ACID HEMISODIUM SALT
  • 4-(2-HYDROXYETHYL)PIPERAZINE-1-ETHANESULFONIC ACID HEMISODIUM SALT
  • 4-(2-HYDROXYETHYL)PIPERAZINE-1-ETHANESULFONIC ACID SODIUM SALT
CAS:
103404-87-1
MF:
C8H19N2NaO4S
MW:
262.3
EINECS:
688-394-6
Product Categories:
  • Pharmaceutical Intermediates
  • buffer
Mol File:
103404-87-1.mol
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4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid hemisodium salt Chemical Properties

storage temp. 
room temp
solubility 
H2O: 1 M at 20 °C, clear, colorless
form 
dry powder
pka
7.5
color 
White to off-white
PH
7.4-7.7 (25°C, 0.1M in water)
PH Range
6.8 - 8.2
biological source
synthetic
Water Solubility 
Soluble in water.
InChI
1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1
InChIKey
RDZTWEVXRGYCFV-UHFFFAOYSA-M
SMILES
[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
3-10
HS Code 
29335990
Storage Class
11 - Combustible Solids

MSDS

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4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid hemisodium salt Usage And Synthesis

Chemical Properties

White solid

Uses

HEPES hemisodium salt is common buffer for biological sciences, particularly used in cell culture to maintain physiological pH. It acts a buffering component, which is used in the preparation of buffers. It is described as one of the best all-purpose buffers available for use in biological research.

Definition

ChEBI: Sodium 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate is an organic sodium salt, a N-(2-hydroxyethyl)piperazine and a N-(sulfoalkyl)piperazine. It contains a 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate.

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