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ChemicalBook >  Product Catalog >  Organic Chemistry >  Amides >  1,3,5-Tris[3-(dimethylamino)propyl]hexahydro-1,3,5-triazine

1,3,5-Tris[3-(dimethylamino)propyl]hexahydro-1,3,5-triazine

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1,3,5-Tris[3-(dimethylamino)propyl]hexahydro-1,3,5-triazine Basic information

Product Name:
1,3,5-Tris[3-(dimethylamino)propyl]hexahydro-1,3,5-triazine
Synonyms:
  • 3,3',3''-(1,3,5-triazinane-1,3,5-triyl)tris(N,N-diMethylpropan-1-aMine)
  • 1,3,5-tris(diMethylaMinopropyl)hexahydro-s- triazine (s-triazine)
  • n,n’,n’’-tris(dimethylaminopropyl)-s-hexahydrotriazine
  • niaxc41
  • polycat41
  • polycatp41
  • r141
  • r141(catalyst)
CAS:
15875-13-5
MF:
C18H42N6
MW:
342.58
EINECS:
240-004-1
Product Categories:
  • Trimerization catalyst for hard foam with high moisture,reduce removing time
  • Organics
Mol File:
15875-13-5.mol
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1,3,5-Tris[3-(dimethylamino)propyl]hexahydro-1,3,5-triazine Chemical Properties

Melting point:
268-271 °C
Boiling point:
141-142°C
Density 
0.92
vapor pressure 
5.332hPa at 21.1℃
refractive index 
1.478
Flash point:
>110°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
10.00±0.28(Predicted)
form 
transparent viscous liquid
color 
Colorless to light yellow
Water Solubility 
590g/L at 25℃
LogP
0.26 at 25℃
CAS DataBase Reference
15875-13-5(CAS DataBase Reference)
EPA Substance Registry System
1,3,5-Triazine-1,3,5(2H,4H,6H)-tripropanamine, N,N,N',N',N'',N''-hexamethyl- (15875-13-5)
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Safety Information

Hazard Codes 
C
Risk Statements 
21-34
Safety Statements 
26-27-36/37/39-45
RIDADR 
2735
RTECS 
XY9491300
HazardClass 
8
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1,3,5-Tris[3-(dimethylamino)propyl]hexahydro-1,3,5-triazine Usage And Synthesis

Uses

1,3,5-Tris[3-(dimethylamino)propyl]hexahydro-1,3,5-triazine is a moderately active trimerisation catalyst. It has very good foaming ability. It has very good performance in water co-blown rigid systems. It can be widely used in rigid polyurethanes, polyisocyanurate foams and non-foams.

Synthesis

50-00-0

109-55-7

15875-13-5

General procedure for the synthesis of tris(dimethylaminopropyl)hexahydrotriazine from formaldehyde and N,N-dimethyl-1,3-diaminopropane: To a 125 mL round-bottomed flask was added a solution of N,N-dimethylpropane-1,3-diamine (6.29 mL, 50 mmol) in toluene (15 mL), followed by paraformaldehyde (1.652 g, 55 mmol, 1.1 eq.) . A Dean-Stark manifold was installed and the reaction mixture was refluxed for 1.5 hours. After completion of the reaction, toluene was removed by evaporation. A portion of the residue (1.9757 g) was taken and partitioned between chloroform (15 mL) and water (5 mL). The organic layer was separated, dried over anhydrous magnesium sulfate and concentrated to give a clarified oily product. The product yield was 66% (1.3067 g). Thin layer chromatography (TLC) analytical conditions: unfolding agent was a 20% ethyl acetate solution of methanol (10 mL) with an Rf value of 0.05. Nuclear magnetic resonance hydrogen spectrum (1H NMR, 400 MHz, CDCl3, δ): 3.29 (broad peak, 6H, H5), 2.40 (triple peak, 6H, J = 7.5 Hz, H4), 2.25 (triple peak, 6H, J = 7.5 Hz, H3), 2.18 (single peak, 18H, H2), 1.59 (multiple peaks, 6H, J = 7.5 Hz, H1) ppm. nuclear magnetic resonance carbon spectrum (13C NMR, 100 MHz, CDCl3, δ): 74.65 (C5), 57.83 (C3), 50.78 (C4), 45.54 (C2), 25.88 ( C1) ppm.

References

[1] Patent: WO2014/127451, 2014, A1. Location in patent: Page/Page column 53; 54
[2] Patent: WO2004/43938, 2004, A1. Location in patent: Page 4

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