Thalidomide-O-C6-NH2 TFA Chemical Properties

storage temp. 

2-8°C, protect from light

form 

Solid

color 

Light green to green

Thalidomide-O-C6-NH2 TFA Usage And Synthesis

Uses

Thalidomide-4-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13 (HY-114421), a degrader of FKBP12F36V and BET[1].

IC 50

Cereblon

References

[1] Erb MA, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 2017 Mar 9;543(7644):270-274. DOI:10.1038/nature21688

Thalidomide-O-C6-NH2 TFA(1957235-99-2)Related Product Information

• Thalidomide-O-C10-NH2
• Thalidomide-4-O-C8-NH2
• Thalidomide-O-C5-acid
• Thalidomide-4-O-C6-NH2 hydrochloride
• Thalidomide-O-C3-acid
• Thalidomide-O-C6-acid
• Thalidomide-O-C5-NH2
• Thalidomide-linker 9
• Thalidomide-linker 6
• Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
• Propanoic acid, 3-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
• 1H-Isoindole-1,3(2H)-dione, 4-[(7-aminoheptyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-
• Thalidomide-O-C6-NH2
• Thalidomide-O-amido-C4-NH2 hydrochloride
• Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
• Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
• Thalidomide-O-amido-C3-NH2 (TFA)