ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > Crisaborole intermediate
Crisaborole intermediate
Crisaborole intermediate Basic information
- Product Name:
- Crisaborole intermediate
- Synonyms:
-
- 5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
- Crisaborole Impurity 59
- 5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol
- Crisaborole Impurity 37
- Crisaborole Impurity 28
- Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
- Creborol Impurity 28
- CAS:
- 1187188-60-8
- MF:
- C14H13BO4
- MW:
- 256.06
- Mol File:
- 1187188-60-8.mol
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Crisaborole intermediate Chemical Properties
- Boiling point:
- 432.1±55.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- pka
- 7.05±0.20(Predicted)
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Crisaborole intermediate Usage And Synthesis
Uses
5-(4-(Hydroxyl Methyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol is an impurity for Crisaborole(H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.
Crisaborole intermediateSupplier
Beijing Comparison Pharmaceutical Technology Co., Ltd
- Tel
- 010-010-52878169 15801002657
- sales@bjcomparison.com
ChemStrong Scientific Co.,Ltd
- Tel
- 0755-0755-66853366 13670046396
- sales@chem-strong.com
Hubei Yangxin Medical Technology Co., Ltd.
- Tel
- 15374522761
- 3003392093@qq.com
TOSUN PHARM
- Tel
- 020-61855200 13326451905
- 260366801@qq.com
ANHUI WITOP BIOTECH CO., LTD
- Tel
- +8615255079626
- eric@witopchemical.com