Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Bulk Drug Intermediates >  (1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

Basic information Safety Supplier Related

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Basic information

Product Name:
(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
Synonyms:
  • Pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione, 7-chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-, (1R)-
  • 7-chloro-6-fluoro-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
  • (1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
  • (1R)-7-Chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS:
2300966-23-6
MF:
C16H14ClFN4O2
MW:
348.76
Mol File:
2300966-23-6.mol
More
Less

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Chemical Properties

Density 
1.397±0.06 g/cm3(Predicted)
pka
6.91±0.20(Predicted)
InChI
InChI=1S/C16H14ClFN4O2/c1-7(2)11-12(8(3)4-5-19-11)22-14-9(15(23)21-16(22)24)6-10(18)13(17)20-14/h4-7H,1-3H3,(H,21,23,24)
InChIKey
OXJTVPMAMRSGNT-UHFFFAOYSA-N
SMILES
O=C1NC(=O)C2=CC(F)=C(Cl)N=C2N1C1C(=CC=NC=1C(C)C)C
More
Less

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Usage And Synthesis

Definition

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione is an intermediate of Sotorasib which is used to treat a particular type of lung cancer.

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dioneSupplier

Heading (Nanjing)Pharmtechnologies Co., Ltd. Gold
Tel
025-58467899-832 13382406280
Email
liucheng@headingpharm.com
Shanghai Hope Chem Co., Ltd., Gold
Tel
+21-18501659228 18501659228
Email
info@hope-chem.com
Suzhou Ryan Pharmaceutical Technology Co., Ltd.
Tel
0512-68780025 18962125825
Email
sales@ryanchem.com
Suli Pharmaceutical Technology Co., Ltd.
Tel
021-58086325-8060 13636568474
Email
yingjie.zhang@suli.com
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com