2-Chloro-4-nitrophenol Chemical Properties

Melting point:

105-106 °C (lit.)

Boiling point:

290.6±25.0 °C(Predicted)

Density 

1.4914 (rough estimate)

vapor pressure 

0.133Pa at 25℃

refractive index 

1.5810 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

form 

Crystalline Powder or Crystals

pka

5.43±0.22(Predicted)

color 

White to beige

Water Solubility 

slightly soluble

BRN 

2046372

InChI

1S/C6H4ClNO3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H

InChIKey

BOFRXDMCQRTGII-UHFFFAOYSA-N

SMILES

Oc1ccc(cc1Cl)[N+]([O-])=O

LogP

2.55

CAS DataBase Reference

619-08-9(CAS DataBase Reference)

NIST Chemistry Reference

2-Chloro-4-nitrophenol(619-08-9)

EPA Substance Registry System

Phenol, 2-chloro-4-nitro- (619-08-9)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38-22

Safety Statements 

26-36-37/39

RIDADR 

2811

WGK Germany 

3

RTECS 

SK5075000

TSCA 

TSCA listed

HS Code 

29089000

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:2-Chloro-4-nitrophenol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Chloro-4-nitrophenol Usage And Synthesis

Chemical Properties

white to beige crystalline powder or crystals

Uses

2-Chloro-4-nitrophenol, is frequently used as building blocks for dyes, plastics, explosives. It acts as a catalytic agent, petrochemical additive and used in organic synthesis. It can react with sulfuric acid dimethyl ester to produce 2-chloro-4-nitro-anisole. This reaction will need reagents K2CO3 and xylene.

Flammability and Explosibility

Not classified

Synthesis

In the 500 ml four-necked bottle equipped with a thermometer, stirrer, reflux condenser and tail gas absorption device plus add 60 grams of 99% p-nitrophenol (0.427 mole) and 240 grams of solvent dichloroethane, stirring and heated to 55-65 ??, the opening of the vacuum tail gas absorption system to ensure that the micro-negative -0.01-0.02MPa conditions, and then pass into the chlorine, the use of GC tracking Reaction process, until the raw material reaction is completed. First of all, atmospheric pressure desolvation and recovery of solvent dichloroethane direct set of use, and then decompression at 10mmHg distillation residual solvent dichloroethane recovery set of steam, to obtain the crude o-chloro-p-nitrophenol, cooled down to 50 ?? C to the following plus 200 grams of toluene, warmed up to the full solubility of the natural precipitation of the temperature is slowly lowered, and then the ice bath cooling to (0-5) ?? C stirring for an hour and then add filtration, drying to get 71.5 grams of 2-chloro-4-nitrophenol, 95.1% yield, GC tracking. Yield 95.1%, GC qualitative content of 99%.

2-Chloro-4-nitrophenol(619-08-9)Related Product Information

• 2-Chloro-4-nitrobenzoic acid
• 4-tert-Butyl-2-nitrophenol
• 4-Chlorophenol
• 4-CHLORO-2-NITROPHENOL
• 2,6-Dichloro-4-nitrophenol
• 3,5-DICHLORO-4-(2-CHLORO-4-NITROPHENOXY)BENZENE-1-SULFONYL CHLORIDE
• 2-AMIO-6-CHLORO-4-NITROPHENOL,2-AMINO-6-CHLORO-4-NITROPHENOL,-Amino-6-Chloro-4-Nitrophenol
• 2,6-DICHLORO-4-NITROANISOLE
• 3-Nitrophenol
• 4-Nitrophenol
• Nitrophenol
• PICRIC ACID
• 2-CHLORO-4,6-DINITROPHENOL
• 2-Chloro-4-nitoranisole
• 2-Nitrophenol
• Difluorochloromethane
• 2,5-DINITROPHENOL
• 3,4,6-TRICHLORO-2-NITROPHENOL