alpha-Phenylcinnamic acid Chemical Properties

Melting point:

172-174 °C(lit.)

Boiling point:

325.66°C (rough estimate)

Density 

1.198

refractive index 

1.6530 (estimate)

form 

powder to crystal

pka

4.8 in 60% ethanol

color 

White to Almost white

Merck 

14,7281

BRN 

1911342

Stability:

Stable. Incompatible with strong oxidizing agents.

CAS DataBase Reference

91-48-5(CAS DataBase Reference)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29163990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

alpha-Phenylcinnamic acid Usage And Synthesis

Chemical Properties

white to light yellow powder

Uses

α-Phenylcinnamic Acid, is a 2,3-Diarylpropenoic Acid, which is a selective non-steroidal inhibitors of type-5 17β-hydroxysteroid dehydrogenase (AKR1C3).

Synthesis Reference(s)

Journal of the American Chemical Society, 104, p. 321, 1982 DOI: 10.1021/ja00365a073
Organic Syntheses, Coll. Vol. 4, p. 777, 1963

Purification Methods

Crystallise the cis-isomer from pet ether or EtOH (m 174

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