3-Aminobenzoic acid Chemical Properties

Melting point:

178-180 °C(lit.)

Boiling point:

251.96°C (rough estimate)

Density 

1,51 g/cm³

refractive index 

1.5323 (estimate)

Flash point:

150 °C

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

5.9 g/L (15°C)

pka

4.78(at 25℃)

form 

Powder

color 

White-brownish to beige-brown

Odor

Odorless

Water Solubility 

5.9 g/L (15 ºC)

Merck 

14,421

BRN 

471603

LogP

0.650

CAS DataBase Reference

99-05-8(CAS DataBase Reference)

NIST Chemistry Reference

Benzoic acid, 3-amino-(99-05-8)

EPA Substance Registry System

Benzoic acid, 3-amino- (99-05-8)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38

Safety Statements 

26-37/39-36

WGK Germany 

2

RTECS 

DG1225000

TSCA 

Yes

HS Code 

29224995

MSDS

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3-Aminobenzoic acid Usage And Synthesis

Chemical Properties

White to off white crystalline powder

Uses

3-Aminobenzoic acid is used as an intermediate for dyes, pesticides and other organic synthesis.

Uses

It finds its application as crystalline Intermediate for azo dyes, pharmaceuticals, and X-ray contrast media.

Definition

ChEBI: 3-aminobenzoic acid is an aminobenzoic acid carrying an amino group at position 3. It is functionally related to a benzoic acid. It is a conjugate acid of a 3-aminobenzoate.

Preparation

3-Aminobenzoic acid is prepared by the reduction of 3-nitrobenzoic acid and used in dye syntheses. Its derivative N,N-dimethyl-3- aminobenzoic acid is also used in the production of dyes.

General Description

3-Aminobenzoic acid, popularly known as Mesalazine Impurity E, is a related compound of anti-inflammatory agent Mesalazine. Mesalazine belongs to a group of drugs referred to as aminosalicylates and is generally used in the treatment of inflammatory bowel disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Crystallise the acid from water. [Beilstein 14 IV 1092.]

3-Aminobenzoic acid(99-05-8)Related Product Information

• Ethyl 2-(Chlorosulfonyl)acetate
• m-Anisidine
• 3-Aminobenzonitrile
• 4-Amino-3-methylbenzoic acid
• 3,5-Diaminobenzoic acid
• Methyl anthranilate
• Folic acid
• Glycine
• O-AMINOBENZOIC ACID
• P-AMINOBENZOIC ACID
• Fluorescein isothiocyanate
• 4-Chloro-3,5-dinitrobenzoic acid
• 3,5-Dinitrosalicylic acid
• 3-(Dimethylamino)benzoic acid
• 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
• 3-NITRO-1,8-NAPHTHALIC ANHYDRIDE
• Calconcarboxylic acid
• 2-Chloro-3,5-dinitrobenzoic acid