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3-Aminobenzoic acid

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3-Aminobenzoic acid Basic information

Product Name:
3-Aminobenzoic acid
Synonyms:
  • 3-AMINOBENZOIC ACID FOR SYNTHESIS
  • Between the aMino acid
  • 3-Aminobenzoic acid Vetec(TM) reagent grade, 98%
  • 3-Aminobenzoic (>=98.5% OR >= 99%)
  • Mesalamine EP Impurity D
  • 3-Abz-OH
  • 3-Aminobenzoic acid≥ 98.5% (assay)
  • Aminobenzenecarboxylic acid
CAS:
99-05-8
MF:
C7H7NO2
MW:
137.14
EINECS:
202-724-4
Product Categories:
  • AMINOACID
  • Aromatic Amino Acids
  • FINE Chemical & INTERMEDIATES
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • Organic acids
  • bc0001
  • 99-05-8
Mol File:
99-05-8.mol
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3-Aminobenzoic acid Chemical Properties

Melting point:
178-180 °C(lit.)
Boiling point:
251.96°C (rough estimate)
Density 
1,51 g/cm3
refractive index 
1.5323 (estimate)
Flash point:
150 °C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
5.9 g/L (15°C)
pka
4.78(at 25℃)
form 
Powder
color 
White-brownish to beige-brown
Odor
Odorless
Water Solubility 
5.9 g/L (15 ºC)
Merck 
14,421
BRN 
471603
LogP
0.650
CAS DataBase Reference
99-05-8(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 3-amino-(99-05-8)
EPA Substance Registry System
Benzoic acid, 3-amino- (99-05-8)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
2
RTECS 
DG1225000
TSCA 
Yes
HS Code 
29224995

MSDS

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3-Aminobenzoic acid Usage And Synthesis

Chemical Properties

White to off white crystalline powder

Uses

3-Aminobenzoic acid is used as an intermediate for dyes, pesticides and other organic synthesis.

Uses

It finds its application as crystalline Intermediate for azo dyes, pharmaceuticals, and X-ray contrast media.

Definition

ChEBI: 3-aminobenzoic acid is an aminobenzoic acid carrying an amino group at position 3. It is functionally related to a benzoic acid. It is a conjugate acid of a 3-aminobenzoate.

Preparation

3-Aminobenzoic acid is prepared by the reduction of 3-nitrobenzoic acid and used in dye syntheses. Its derivative N,N-dimethyl-3- aminobenzoic acid is also used in the production of dyes.

General Description

3-Aminobenzoic acid, popularly known as Mesalazine Impurity E, is a related compound of anti-inflammatory agent Mesalazine. Mesalazine belongs to a group of drugs referred to as aminosalicylates and is generally used in the treatment of inflammatory bowel disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Crystallise the acid from water. [Beilstein 14 IV 1092.]

3-Aminobenzoic acidSupplier

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