methyl (16alpha,17beta)-17-hydroxyyohimban-16-carboxylate CAS#: 549-84-8

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methyl (16alpha,17beta)-17-hydroxyyohimban-16-carboxylate

Basic information Safety Supplier Related

methyl (16alpha,17beta)-17-hydroxyyohimban-16-carboxylate Basic information

Product Name:

methyl (16alpha,17beta)-17-hydroxyyohimban-16-carboxylate

Synonyms:

methyl (16alpha,17beta)-17-hydroxyyohimban-16-carboxylate
Amsonin
Amsonine
2-hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2-a]$b-carboline-1-carboxylic acid methyl ester
beta-Yohimbine
Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16a,17b)-
β-Yohimbine
Methyl (16?,17?)-17-hydroxyyohimban-16-carboxylate

CAS:

549-84-8

MF:

C21H26N2O3

MW:

354.44

EINECS:

208-977-7

Mol File:

549-84-8.mol

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methyl (16alpha,17beta)-17-hydroxyyohimban-16-carboxylate Usage And Synthesis

Uses

β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A)-resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL)[1].

References

[1] dos Santos Torres ZE, et al. Chemical composition of Aspidosperma ulei Markgr. and antiplasmodial activity of selected indole alkaloids. Molecules. 2013 May 29;18(6):6281-97. DOI:10.3390/molecules18066281

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