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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Bulk Drug Intermediates >  5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester

5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester

Basic information Safety Supplier Related

5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Basic information

Product Name:
5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
Synonyms:
  • 5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
  • TAK788 (AP32788) Intermediate
  • TAK788 Intermediate 3
CAS:
1847463-39-1
MF:
C17H16ClN3O2
MW:
329.78
Mol File:
1847463-39-1.mol
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5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Chemical Properties

Boiling point:
555.2±45.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
pka
-2.43±0.40(Predicted)
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5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Usage And Synthesis

Uses

5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester is an intermediate of TAK-788 which is an orally active and irreversible EGFR/HER2 inhibitor.

5-Pyrimidinecarboxylic acid, 2-chloro-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl esterSupplier

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