Beclomethasone 17-propionate Chemical Properties

Melting point:

124-126?C

Boiling point:

608.9±55.0 °C(Predicted)

Density 

1.30±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

DMSO: 100 mg/mL (215.06 mM)

form 

Solid

pka

12.98±0.10(Predicted)

color 

White to Light Yellow

InChIKey

OHYGPBKGZGRQKT-MVAAQJHONA-N

SMILES

C1(=O)C=C2[C@](C)(C=C1)C1(Cl)[C@]([H])([C@@]3([H])[C@@](C[C@@H]1O)(C)[C@@](OC(=O)CC)(C(=O)CO)[C@@H](C)C3)CC2 |&1:4,10,12,14,16,19,29,r|

Safety Information

HS Code 

29162090

Beclomethasone 17-propionate Usage And Synthesis

Description

Beclomethasone 17-propionate is a glucocorticoid receptor agonist and an active metabolite of the glucocorticoid prodrug beclomethasone dipropionate. It can effectively inhibit cytokine production in lung macrophages of chronic obstructive pulmonary disease (COPD) and can be used in the study of diseases related to respiratory inflammation.

Chemical Properties

Light Yellow Solid

Uses

Active metabolite of Beclomethasone Dipropionate (BDP).

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