alpha-carboline Chemical Properties

Melting point:

210-212°C

Boiling point:

373℃

Density 

1.301

Flash point:

172℃

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Acetone, DMSO, Methanol (Slightly, Hetaed)

form 

Solid

pka

14.53±0.30(Predicted)

color 

Pale Brown

λmax

338nm(CH3CN)(lit.)

InChI

InChI=1S/C11H8N2/c1-2-6-10-8(4-1)9-5-3-7-12-11(9)13-10/h1-7H,(H,12,13)

InChIKey

BPMFPOGUJAAYHL-UHFFFAOYSA-N

SMILES

N1C2=C(C=CC=C2)C2=CC=CN=C12

Safety Information

HS Code 

2933.99.8290

alpha-carboline Usage And Synthesis

Chemical Properties

Light Brown Solid

Uses

A carcinogenic compound formed during cooking processes

Definition

ChEBI: 9H-Pyrido[2,3-b]indole is a pyridoindole.

Synthesis

The 9H-pyrido[2,3- b]indoles were produced by dissolving 1-bromo-2-(2,2-dibromovinyl)benzene or its derivatives, ammonia and a, ??-unsaturated aldehydes in an organic solvent, and then adding a catalyst, transition metal salts and additives, and then reacting at 60-100 ??C in the presence of air. The synthesis process of the present invention is a one-pot multi-component tandem reaction, which is simple and easy to operate, and avoids the waste of resources and environmental pollution caused by the use of a variety of reagents and the purification of intermediates in each step of the reaction, and provides an economical and practical method for the synthesis of 9H-pyrido[2,3-b]indole compounds in a green and environmentally friendly way.

alpha-carboline(244-76-8)Related Product Information

• Exalamide
• 9,10,11-Trioxatetracyclo[6.2.1.02,7.03,6]undecane (8CI,9CI)
• 9H-PYRIDO[3,4-B]INDOLE