D-Aspartic Acid diethyl ester hydrochloride Chemical Properties

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

Appearance

White to off-white Solid

D-Aspartic Acid diethyl ester hydrochloride Usage And Synthesis

Synthesis

Acetyl chloride (54.6 mL, 0.75 mol) was slowly added dropwise to ethanol (316 mL) at 0-5 °C. After the dropwise addition was completed, the ice bath was removed and the reaction solution was continued to be stirred at room temperature for 30 min. Subsequently, D-aspartic acid (19.1, 25 g, 0.188 mol) was added to the reaction system. The reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, the reaction solution was concentrated in vacuum and dried under high vacuum (0.4 mmHg) overnight to afford compound 19.2 (42 g, 99% yield) as a white solid, which can be used in subsequent reactions without further purification.

References

[1] Patent: WO2007/56056, 2007, A2. Location in patent: Page/Page column 75-76

D-Aspartic Acid diethyl ester hydrochloride(112018-26-5)Related Product Information

• H-D-ASP(OBZL)-OH
• D-ASPARTIC ACID-BETA-METHYL ESTER
• H-D-Asp(OEt)-OtBu.Hcl
• H-D-Asp(OtBu)-OMe·HCl
• H-D-Asp(OEt)-OH
• D-ASPARTIC ACID(OBZL)-OBZL P-TOSYLATE
• D-Aspartic acid, 4-(1,1-dimethylethyl) 1-methyl ester
• H-D-Asp(Otbu)-(O-2-PhiPr)
• H-D-Asp(OtBu)-OtBu · HCl
• 4-methyl hydrogen D-aspartate hydrochloride
• D-Aspartic acid