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Piperaquine

Basic information Safety Supplier Related

Piperaquine Basic information

Product Name:
Piperaquine
Synonyms:
  • Piperaquine
  • Brn 0905079
  • Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro- (9ci)
  • Quinoline, 4,4'-(trimethylenedi-4,1-piperazinediyl)bis(7-chloro-
  • Piperaquine USP/EP/BP
CAS:
83764-65-2
MF:
C29H32Cl2N6
MW:
535.51058
Mol File:
83764-65-2.mol
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Piperaquine Usage And Synthesis

Pharmaceutical Applications

A bisquinoline used to treat malaria in China since 1978. It is structurally related to chloroquine, but active against chloroquine- resistant P. falciparum. A combination with dihdyroartemisinin has shown excellent tolerability and high cure rates for multidrug-resistant falciparum malaria.
It is highly lipid-soluble and orally well absorbed. The elimination half-life is 20–30 days and there is extensive metabolism. Adverse effects are similar to chloroquine, but pruritus is uncommon.

PiperaquineSupplier

Guangdong New South Artemisia Science and Technology Co., Ltd. Gold
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Dideu Industries Group Limited
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Shaanxi Dideu Medichem Co. Ltd
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ShangHai Anpel Co, Ltd.
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shanpel@anpel.com.cn
Qingdao haohai anjie pharmaceutical technology co., ltd.
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156-6622-8711 18639325623
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