7-(3-CHLORO-PROPOXY)-4-(2,4-DICHLORO-5-METHOXY-PHENYLAMINO)-6-METHOXY-QUINOLINE-3-CARBONITRILE Chemical Properties

Melting point:

183-186℃

Boiling point:

585.6±50.0 °C(Predicted)

Density 

1.43

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

Chloroform (Slightly, Sonicated), DMSO (Slightly)

form 

Solid

pka

3.71±0.50(Predicted)

color 

Pale Yellow to Light Yellow

7-(3-CHLORO-PROPOXY)-4-(2,4-DICHLORO-5-METHOXY-PHENYLAMINO)-6-METHOXY-QUINOLINE-3-CARBONITRILE Usage And Synthesis

Uses

1-Chloro-1-desmethylpiperazinyl-bosutinib is a useful intermediate in the green preparation of the anti-tumor agent Bosutinib (B676095). It is a COVID19-related research product.

7-(3-CHLORO-PROPOXY)-4-(2,4-DICHLORO-5-METHOXY-PHENYLAMINO)-6-METHOXY-QUINOLINE-3-CARBONITRILE(380844-49-5)Related Product Information

• Bosutinib Impurity 3
• Bosutinib Impurity 4
• Bosutinib Impurity 6
• Bosutinib Impurity 15
• Bosutinib Impurity
• 5-Amino-2,4-dichloroanisole
• 2-aMino-4-(3-chloropropoxy)-5-Methoxybenzoate
• 4-CHLORO-7-(3-CHLORO-PROPOXY)-6-METHOXY-QUINOLINE-3-CARBONITRILE
• Methyl 4-(3-chloropropoxy)-5-Methoxy-2-nitrobenzoate
• Bosutinib
• Bosutinib Monohydrate
• 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-6-methoxy-3-quinolinecarbonitrile
• 3-Quinolinecarbonitrile, 7-(3-chloropropoxy)-4-hydroxy-6-Methoxy-
• 1-[3-(2-Methoxy-5-nitrophenoxy)propyl]-4-Methylpiperazine
• N-(2,4-DICHLORO-5-HYDROXYPHENYL)ACETAMIDE
• 4-Methoxy-3-(3-(4-Methylpiperazin-1-yl)propoxy)aniline
• 4-CHLORO-7-FLUORO-6-METHOXY-QUINOLINE-3-CARBONITRILE
• 4-CHLORO-7-HYDROXY-6-METHOXY-QUINOLINE-3-CARBONITRILE