2-Bromo-5-chloro-3-nitropyridine Chemical Properties

Melting point:

75-78°C

Boiling point:

250.3±35.0 °C(Predicted)

Density 

1.936±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

soluble in Methanol

pka

-5.53±0.20(Predicted)

form 

Solid

color 

Off-white

CAS DataBase Reference

75806-86-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-41-38-22

Safety Statements 

26-36/37/39-39

WGK Germany 

3

HazardClass 

IRRITANT

HazardClass 

6.1

HS Code 

2933399990

2-Bromo-5-chloro-3-nitropyridine Usage And Synthesis

Chemical Properties

Hoar or pale yellow solid

Synthesis

To a solution of 2-Amino-5-chloro-3-nitropyridine (10.0 g, 57.6 mmol) in HBr [(31.0 mL (100%), 286.4 mmol)], sodium nitrite (13.8 g, 199.9 mmol) was added dropwise. To the stirred solution, Br2 (10.0 mL, 197.1 mmol)in water was added and stirred at room temperature for 1 h. The reaction mixture was basified with NaHCO3 solution (PH=7), extracted with ethyl acetate, washed with water, and dried over anhydrous Na2SO4. The solvent was removed under vacuum to yield 2-Bromo-5-chloro-3-nitropyridine (10.0 g, 73.0%) as a yellow solid.

2-Bromo-5-chloro-3-nitropyridine(75806-86-9)Related Product Information

• 3-Bromo-2-chloro-5-nitropyridine 98%,3-BROMO-2-CHLORO-5-NITROPYRIDINE
• 2-Bromo-3-nitropyridine
• 3-AMINO-2-BROMO-5-CHLOROPYRIDINE
• 2-BROMO-3-CHLORO-5-NITROPYRIDINE
• 2-Bromo-4-methylpyridine
• 2-Bromo-5-methylpyridine
• 2-Bromo-6-methyl-3-nitropyridine
• 3-Bromo-2-methoxy-5-nitropyridine
• 2-Chloro-3-bromo-5-methylpyridine
• 2-Bromo-3-methylbenzaldehyde
• 2-Bromo-4-nitroimidazole
• 2-Bromo-4-fluoropyridine
• 2-Bromo-5,6-diphenylpyrazine
• 2-Bromo-3-trifluoromethylpyridine
• 2-Bromo-4-chloropyridine
• 2-Bromo-3-fluoropyridine
• 3-Amino-2-bromopyridine
• 2-Bromopyridine-4-carboxylic acid