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4-MALEIMIDOBUTYRIC ACID

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4-MALEIMIDOBUTYRIC ACID Basic information

Product Name:
4-MALEIMIDOBUTYRIC ACID
Synonyms:
  • γ-Maleimidobutyric acid, 4-Maleimidobutanoic acid, N-(3-Carboxypropyl)maleimide, N-Maleoyl-4-aminobutyric acid, N-Maleoyl-GABA
  • 4-Maleimidobutyric acid,γ-Maleimidobutyric acid, 4-Maleimidobutanoic acid, N-(3-Carboxypropyl)maleimide, N-Maleoyl-4-aminobutyric acid, N-Maleoyl-GABA
  • 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-butanoic Acid
  • 2-Cyclopropyl-5,6,7,8-tetrahydropyrido[4,3-d]pyriMidine hydrochloride
  • MBA 4-Maleimidobutyric acid
  • omega-Maleimidobutyric acid
  • 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
  • Maleimide-(CH2)3-COOH
CAS:
57078-98-5
MF:
C8H9NO4
MW:
183.16
EINECS:
611-461-8
Product Categories:
  • MTS & Sulfhydryl Active Reagents
  • Maleimide Derivatives
  • Nitric Oxide Reagents
  • Cross Linking Reagents
Mol File:
57078-98-5.mol
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4-MALEIMIDOBUTYRIC ACID Chemical Properties

Melting point:
95-98 °C
Boiling point:
400.1±28.0 °C(Predicted)
Density 
1.395±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
pka
4.59±0.10(Predicted)
form 
Solid
color 
White to Pale Yellow
BRN 
1455876
CAS DataBase Reference
57078-98-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
10-21
HS Code 
29251900

MSDS

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4-MALEIMIDOBUTYRIC ACID Usage And Synthesis

Description

4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Chemical Properties

White Solid

Uses

4-Maleimidobutyric Acid is a short crosslinking reagent.

Uses

  1. A short crosslinking reagent
  2. Modification reagent for thiol groups in proteins
  3. Maleimide Derivatives
  4. MTS & Sulfhydryl Active Reagents

4-MALEIMIDOBUTYRIC ACID Preparation Products And Raw materials

Raw materials

4-MALEIMIDOBUTYRIC ACIDSupplier

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