2-Methyl-2-thiopseudourea sulfate CAS#: 867-44-7

2-Methyl-2-thiopseudourea sulfate Basic information

Product Name:

2-Methyl-2-thiopseudourea sulfate

Synonyms:

s-methylthiouroniumsulfate(2:1)
S-METHYL-ISO-THIOUREA
S-MethyliSothourea Sulfate
S-METHYLISOTHIOUREA HEMISULFATE NITRIC O XIDE SYNTHASE
S-Methylthioureasulfate=2-Methyl-2-thiopseudoureasulfate
2-Methyl-2-thiopseudourea sulphate
S-EIT hemihydrate
S-Methylisothiouroniumsulfate,98%

CAS:

867-44-7

MF:

C2H8N2O4S2

MW:

188.23

EINECS:

212-759-7

Product Categories:

Cell Signaling and Neuroscience
Nitric Oxide and Cell Stress
Nitric Oxide Metabolism
Nitric Oxide Synthase Regulators
Bioactive Small Molecules
Building Blocks
pharmacetical
Nitric Oxide
Cell Biology
Chemical Synthesis
M
Organic Building Blocks
Sulfur Compounds
Thioureas

Mol File:

867-44-7.mol

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2-Methyl-2-thiopseudourea sulfate Chemical Properties

Melting point:: 240-241 °C (dec.)(lit.)
Density: 1.28
Flash point:: 3℃
storage temp.: Inert atmosphere,Room Temperature
solubility: H₂O: 0.1 g/mL, clear, colorless
pka: pK1:9.83(＋1) (25°C)
form: Crystals or Crystalline Powder
color: White
PH: 5.5 (260g/l, H2O, 20℃)
Water Solubility: 260 g/L (20 ºC)
Sensitive: Hygroscopic
BRN: 3917217
Stability:: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 867-44-7(CAS DataBase Reference)
EPA Substance Registry System: Carbamimidothioic acid, methyl ester, sulfate (2:1) (867-44-7)

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Safety Information

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 22-24/25
WGK Germany: 3
RTECS: UM9200000
TSCA: Yes
HS Code: 29309070

MSDS

Language:English Provider:2-Methyl-2-thiopseudourea sulfate

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2-Methyl-2-thiopseudourea sulfate Usage And Synthesis

Description

SMIT is a potent non-selective inhibitor of NOS isoforms in vitro but may lack good in vivo efficacy due to poor cellular penetration. The K_i values are 120, 200, and 160 nM using purified human iNOS, eNOS, and nNOS, respectively.

Chemical Properties

white crystalline powder

Uses

Intermediate of 4-Hydroxydebrisoquine. S-Methyl-isothiouronium Hemisulfate is also a reagent used in the synthesis of strobilurin-pyrimidine derivatives for their anti-proliferative activity.

Biochem/physiol Actions

More potent than NMMA as an inhibitor of inducible nitric oxide synthetase (iNOS).

2-Methyl-2-thiopseudourea sulfate Preparation Products And Raw materials

Preparation Products

5-methoxy-2-(methylthio)pyrimidin-4-ol ,97%4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile ,97%1-Methyl-3-nitro-1-nitrosoguanidine 4-AMINO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Aminoguanidine bicarbonate 1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER IMINOCTADINE TRIACETATE 5-CHLORO-2-METHOXYPYRIMIDINE-4-CARBOXYLIC ACID 1,1-DIMETHYLGUANIDINE SULFATE 5-[2-(METHYLTHIO)PYRIMIDIN-4-YL]THIOPHENE-2-SULFONYL CHLORIDE 5-Chloro-2-(methylsulfonyl)pyrimidine METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 4-Methoxy-6-methyl-2-(methylsulfonyl)pyrimidine ,97%5-CHLORO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 5-Bromo-4-chloro-2-(methylthio)-7H-pyrrolo[2,3-D]pyrimidine ,97%5-BROMO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 2-(METHYLTHIO)-4-(TRIFLUOROMETHYL)PYRIMIDINE 4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97%4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile ,97%3-OXO-3-THIOPHEN-2-YL-PROPIONIC ACID ETHYL ESTER 5-AMINOPYRIMIDINE 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate 4-Methoxy-6-methyl-2-(methylthio)pyrimidine 4-METHYL-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 2-(METHYLSULFANYL)-5-PHENYLPYRIMIDINE 5-Methyl-2-(methylsulfonyl)pyrimidine ,97%Aminoguanidinium sulphate 2-(METHYLTHIO)ETHANOL 1-(4-METHYL-2-(METHYLTHIO)PYRIMIDIN-5-YL)ETHANONE Gabexate mesylate 4-AMINO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL 2-(ETHYLTHIO)-4-HYDROXYPYRIMIDINE-5-CARBOXYLATE 5-METHYL-2-METHYLSULFANYL-PYRIMIDINE 4-Chloro-6-methyl-2-(methylthio)pyrimidine

2-Methyl-2-thiopseudourea sulfateSupplier

Zhaoyuan Chaoda Chemical Ltd. Gold

Tel: 13964589815
Email: phx8415088@163.com

Nanjing Yili Biotechnology Co., Ltd. Gold

Tel: 18061293607
Email: 2880300874@qq.com

Jinan Londi Medical Technology Co., LTD Gold

Tel: 0531-88996911 15628983711
Email: 3305202763@qq.com

Zheda Panaco Chemical Engineering Co., Ltd Gold

Tel: 0571-86770761
Email: zhedapanaco02@zhedachem.com

Zheda Panaco (Shandong) Chemical Enginering Co., Ltd. Gold

Tel: 0530-8865559 13805730994;
Email: panaco@zhedachem.com

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