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6-Bromo-2-naphthyl α-D-galactopyranoside

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6-Bromo-2-naphthyl α-D-galactopyranoside Basic information

Product Name:
6-Bromo-2-naphthyl α-D-galactopyranoside
Synonyms:
  • 6-BROMO NAPHTHYL GALACTOPYRANOSIDE
  • 6-BROMO-2-NAPHTHYL-A-D-GALACTOPYRANOSIDE
  • 6-BROMO-2-NAPHTHYL-ALPHA-D-GALACTOPYRANOSIDE
  • 2-(6-BROMONAPHTHYL)-ALPHA-D-GALACTOPYRANOSIDE
  • BR-NAP-ALPHA-D-GAL
  • BROMO-2-NAPHTHYL-A-D-GALACTOPYRANOSIDE, 6-
  • 6-Bromo-2-Naphthyl-Alpha-D-Galactopyran-
  • (6-Bromo-2-naphthalenyl)α-D-galactopyranoside
CAS:
25997-59-5
MF:
C16H17BrO6
MW:
385.21
EINECS:
247-398-4
Product Categories:
  • Substrates
  • 13C & 2H Sugars
  • Carbohydrates & Derivatives
  • substrate
Mol File:
25997-59-5.mol
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6-Bromo-2-naphthyl α-D-galactopyranoside Chemical Properties

Melting point:
225°C
Boiling point:
609℃
Density 
1.698
Flash point:
322℃
solubility 
soluble in Methanol, Water
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Safety Information

HS Code 
29389090
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6-Bromo-2-naphthyl α-D-galactopyranoside Usage And Synthesis

Uses

6-Bromo-2-naphthyl α-D-galactopyranoside can be acted as a useful reagent for determination of alpha-D-Galactosidase activity.

Definition

ChEBI: An alpha-D-galactoside having a 6-bromo-2-naphthyl substituent at the anomeric position.

Purification Methods

It is prepared from penta-O-acetyl-D-galactoside, 6-bromo-2naphthol and ZnCl2. The resulting tetra-acetate (2g) is hydrolysed by dissolving in 0.3N KOH (100mL) and heating until the solution is clear, then filtering and cooling to give colourless crystals of the -isomer which are collected and recrystallised twice from hot MeOH. The high specific rotation is characteristic of the isomer. The tetraacetate has m 155-156o, [] D 20 +60o (c 1, CHCl3) [Dey & Pridham Biochem J 115 47 1969] [reported m 75-85o, [] D 24 +94o (c 1.3, dioxane), Monis et al. J Histochem Cytochem 11 653 1963]. [Beilstein 17 IV 2972.]

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