ChemicalBook > Product Catalog > API > Synthetic Anti-infective Drugs > Antifungal Drugs > Octenidine
Octenidine
Octenidine Basic information
- Product Name:
- Octenidine
- Synonyms:
-
- N，N’-[1，10-Decanediyldi-1(4H)-pyridinyl-4-ylidene]-bis(1-octanamine)
- NeoKodan
- Octeniderm
- Octenisept
- Win-41464
- Win-41464-2
- 1,1'-Decamethylenebis(1,4-dihydro-4-(octylimino)pyridine)
- 1,1'-(1,10-Decanediyl)bis[1,4-dihydro-4-(octylimino)pyridine]
- CAS:
- 71251-02-0
- MF:
- C36H62N4
- MW:
- 550.9
- Mol File:
- 71251-02-0.mol
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Octenidine Chemical Properties
- Boiling point:
- 609.3±55.0 °C(Predicted)
- Density
- 0.94±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.60±0.70(Predicted)
- InChIKey
- ZVXNYZWXUADSRV-UHFFFAOYSA-N
- SMILES
- C(N1C=C/C(=N/CCCCCCCC)/C=C1)CCCCCCCCCN1C=C/C(=N/CCCCCCCC)/C=C1
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Octenidine Usage And Synthesis
Chemical Properties
Octenidine Hydrochloride: C36H62N4?2HCl [70775-75-6]. Obtained as a solid from diethyl ether, melting point 215-217°C.
Uses
Anti-infective, topical.
Definition
ChEBI: Octenidine is a dihydropyridine.
in vivo
Octenidine reduces bacterial counts on mice wounds and inhibit meticillin-resistant Staphylococcus aureus (MRSA)[3].
| Animal Model: | Mice (a six-millimetre punch full-thickness wound was inoculated with MRSA suspension)[3] |
| Dosage: | |
| Administration: | Administrated once 24 hours post-wounding |
| Result: | Accelerated healing and reduced by >3.6 log cfu/g bacterial counts on the wounds relative to the PBS-treated control. Exhibited lower burden of the inflammatory cells, more mature collagen fibres and well-defined epithelialisation. Inhibited the expression of MRSA and its biofilm genes by nearly 100%. |
Octenidine Preparation Products And Raw materials
Raw materials
OctenidineSupplier
Shandong Welt Chem. Co .Ltd Gold
- Tel
- 531-87153728 13805401165
- xufeng192@126.com
Shandong Welt Chem. Co.,Ltd. Gold
- Tel
- 531-87153728 13805401165
- xufeng192@126.com
Shanghai Longsheng chemical Co.,Ltd.
- Tel
- 021-58099652-8005 13585536065
- bin.wu@shlschem.com
Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel
- 0571-82693216
- info@yuhaochemical.com
Beijing HuaMeiHuLiBiological Chemical
- Tel
- 010-56205725
- waley188@sohu.com