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2-(2-HYDROXYPHENYL)BENZOXAZOLE

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2-(2-HYDROXYPHENYL)BENZOXAZOLE Basic information

Product Name:
2-(2-HYDROXYPHENYL)BENZOXAZOLE
Synonyms:
  • 2-(1,3-Benzoxazol-2-yl)phenol
  • 2-(2-benzoxazolyl)-pheno
  • 2-(O-Hydroxyphenyl)benzoxazol
  • 2-(ortho-Hydroxyphenyl)-benzoxazole
  • 2-benzoxazol-2-ylphenol
  • o-(2-Benzoxazolyl)phenol
  • Phenol, o-2-benzoxazolyl-
  • USAF ek-6754
CAS:
835-64-3
MF:
C13H9NO2
MW:
211.22
EINECS:
212-642-0
Product Categories:
  • Fluorescent
  • Building Blocks
  • Heterocyclic Compounds
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Heterocyclic Building Blocks
  • Oxazoles
Mol File:
835-64-3.mol
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2-(2-HYDROXYPHENYL)BENZOXAZOLE Chemical Properties

Melting point:
122-124 °C(lit.)
Boiling point:
338 °C(lit.)
Density 
1.1868 (rough estimate)
refractive index 
6.71E-13 (355 nm)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Solubility Insoluble in water; soluble in ethanol
form 
Solid
pka
8.04(at 25℃)
color 
Light yellow to Brown
PH Range
Non0 uorescence (<9.3) to blue-violet 0 uorescence (9.3)
Major Application
Electroluminescent devices, sensors, plastic scintillation applications, antitumor agent, antibacterial agent
InChI
InChI=1S/C13H9NO2/c15-11-7-3-1-5-9(11)13-14-10-6-2-4-8-12(10)16-13/h1-8,15H
InChIKey
GHGZVWOTJDLREY-UHFFFAOYSA-N
SMILES
C1(O)=CC=CC=C1C1=NC2=CC=CC=C2O1
CAS DataBase Reference
835-64-3(CAS DataBase Reference)
EPA Substance Registry System
Phenol, 2-(2-benzoxazolyl)- (835-64-3)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
SJ7520000
HazardClass 
IRRITANT
HS Code 
29349990

MSDS

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2-(2-HYDROXYPHENYL)BENZOXAZOLE Usage And Synthesis

Chemical Properties

pink to reddish crystalline powder

Definition

ChEBI: 2-(1,3-benzoxazol-2-yl)phenol is a member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole substituted by a 2-hydroxyphenyl group at position 2. It has a role as a geroprotector. It is a member of phenols and a member of 1,3-benzoxazoles.

Purification Methods

Recrystallise it several times from aqueous EtOH or dilute AcOH and sublime it. An aqueous alkaline solution containing EtOH has a blue fluorescence. [Itoh & Fujiwara J Am Chem Soc 107 1561 1985, Beilstein 27 II 91.]

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