Basic information Safety Supplier Related

Defluoro Atorvastatin

Basic information Safety Supplier Related

Defluoro Atorvastatin Basic information

Product Name:
Defluoro Atorvastatin
Synonyms:
  • (bR,dR)-b,d-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid
  • Defluoro Atorvastatin
  • Defluoro atorvastatin calcium salt
  • Atorvastatin Calcium Hydrate Impurity A
  • (betaR,deltaR)-beta,delta-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid
  • 1H-Pyrrole-1-heptanoicacid, b,d-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-,(bR,dR)-
  • Atorvastatin EP IMP A
  • Atorvastatin Impurity 26(Atorvastatin EP Impurity A)
CAS:
433289-84-0
MF:
C33H36N2O5
MW:
540.656
Mol File:
433289-84-0.mol
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Defluoro Atorvastatin Chemical Properties

Melting point:
>193°C (dec.)
Boiling point:
723.7±60.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly, Heated)
form 
Solid
pka
4.29±0.10(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Defluoro Atorvastatin Usage And Synthesis

Uses

Desfluoroatorvastatin is an impurity of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

Definition

ChEBI: Defluoroatorvastatin is a member of pyrroles.

Defluoro AtorvastatinSupplier

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