Basic information Safety Supplier Related

Mitomycin A

Basic information Safety Supplier Related

Mitomycin A Basic information

Product Name:
Mitomycin A
Synonyms:
  • [(1aS,8S,8aR,8bS)-6,8a-Dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2,3,4]pyrrolo[1,2-a]indol-8-yl]methyl Carbamate
  • [(1aS,8S,8aR,8bS)-6,8a-Dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2,’3’:3,4]pyrrolo[1,2-a]indol-8-yl]methyl Carbamate
  • (1aS,8S,8aR,8bS)-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-6,8a-dimethoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
  • ((1aS,8S,8aR,8bS)-6,8a-dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2,3:3,4]pyrrolo[1,2-a]indol-8-yl)methyl carbamate(WXG00529)
  • Mitomycin EP Impurity B
  • Mitomycin Impurity 2(Mitomycin EP Impurity B)(Mitomycin A)
  • Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-6,8a-dimethoxy-5-methyl-, (1aS,8S,8aR,8bS)-
  • Mitomycin EP Impurity B (Mitomycin A)
CAS:
4055-39-4
MF:
C16H19N3O6
MW:
349.34
Product Categories:
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocycles
Mol File:
4055-39-4.mol
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Mitomycin A Chemical Properties

Melting point:
159-1610C (dec)
Boiling point:
483.53°C (rough estimate)
Density 
1.2205 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
-20°C Freezer
solubility 
Chloroform: Slightly soluble; Methanol: Slightly soluble
form 
A solid
pka
13.27±0.50(Predicted)
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Safety Information

Hazardous Substances Data
4055-39-4(Hazardous Substances Data)
Toxicity
LD50 i.v. in mice: 2 mg/kg (Hata, 1956; Kinoshita)
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Mitomycin A Usage And Synthesis

Chemical Properties

Red-Violet Crystals

Uses

The 6-methoxy analog of Mitomycin C. An antitumor antibiotic

Definition

ChEBI: A member of the family of mitomycins that exhibits antibiotic and antitumour properties as well as a high level of toxicity.

Mitomycin ASupplier

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