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N-Desmethyl Tamoxifen Hydrochloride

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N-Desmethyl Tamoxifen Hydrochloride Basic information

Product Name:
N-Desmethyl Tamoxifen Hydrochloride
Synonyms:
  • N-Demethyltamoxifen Hydrochlorid
  • (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride
  • Nsc372964
  • 2-[4-[(1Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N-methylethanamine hydrochloride
  • (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine
  • Tamoxifen Citrate EP Impurity F HCl
  • 2-[4-[(Z)-1,2-Diphenylbut-1-enyl]ph
  • Tamoxifen EP Impurity F HCl
CAS:
15917-65-4
MF:
C25H27NO.ClH
MW:
393.955
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Various Metabolites and Impurities
  • Pharmaceuticals
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
15917-65-4.mol
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N-Desmethyl Tamoxifen Hydrochloride Chemical Properties

Melting point:
225-227°C
storage temp. 
room temp
solubility 
DMSO: ≥20mg/mL
form 
solid
color 
White to off-white
Stability:
Light sensitive
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Safety Information

Hazard Codes 
T,N
Risk Statements 
45-46-60-50/53
Safety Statements 
53-45-60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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N-Desmethyl Tamoxifen Hydrochloride Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

A main metabolite of the anti-cancer drug Tamoxifen (T006000).

Uses

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

Biochem/physiol Actions

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

N-Desmethyl Tamoxifen HydrochlorideSupplier

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