Etybenzatropine
Etybenzatropine Basic information
- Product Name:
- Etybenzatropine
- Synonyms:
-
- Ethylbenatropine
- Ponalide
- UK-738
- VK-738
- Etybenzatropine
- ethybenztropine
- 8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-ethyl-, (3-endo)-
- Etybenzatropine USP/EP/BP
- CAS:
- 524-83-4
- MF:
- C22H27NO
- MW:
- 321.461
- Mol File:
- 524-83-4.mol
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Etybenzatropine Chemical Properties
- Boiling point:
- 460.2°C (rough estimate)
- Density
- 1.0454 (rough estimate)
- refractive index
- 1.5614 (estimate)
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Etybenzatropine Usage And Synthesis
Uses
Anticholinergic.
Definition
ChEBI: Etybenzatropine is a diarylmethane.
brand name
Panolid (Novartis).
in vivo
Ethybenztropine (25 μg, microinjected into mesencephalic NRM) blocks the hypertherrnic response of carbachol microinjection into nucleus raphe median (NRM) of rabbits[1].
Ethybenztropine (30-60 μg/kg, administered by the fourth ventricle) is effective in preventing arrhythmias in dogs[2].
Ethybenztropine (50 mg/kg, i.p.) reduces the catecholamines accumulation in rats[3].
| Animal Model: | Dogs with cardiac arrhythmias[2] |
| Dosage: | 30-60 μg/kg |
| Administration: | Administered by the fourth ventricle |
| Result: | Produced slight hypotension (never exceeding a fall of 25 mm Hg) and slight sinus tachycardia. Converted arrhythmias to sinus rhythms. |
EtybenzatropineSupplier
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
Dideu Industries Group Limited
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
TargetMol Chemicals Inc.
- Tel
- 15002134094
- marketing@targetmol.cn
TargetMol Chemicals Inc.
- Tel
- +17819995354
- marketing@targetmol.com