Basic information Safety Supplier Related

6-AZAURIDINE 2',3',5'-TRIACETATE

Basic information Safety Supplier Related

6-AZAURIDINE 2',3',5'-TRIACETATE Basic information

Product Name:
6-AZAURIDINE 2',3',5'-TRIACETATE
Synonyms:
  • 2μ,3μ,5μ-Tri-O-acetyl-6-azauridine, 6-Azauridine 2μ,3μ,5μ-triacetate, 6-AzUrd-TA, Azaribine, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2μ,3μ,5μ-triacetate
  • 6-Azauridine 2μ,3μ,5μ-triacetate, 6-AzUrd-TA, Azaribine
  • 2-(2-O,3-O,5-O-Triacetyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
  • 6-Azauridine 2',3',5'-triacetate,98%
  • 2-(2’,3’,5’-triacetyl-beta-d-ribofuranosyl)-as-triazine-3,5-(2h,4h)-dione
  • 2’,3’,5’-triacetyl-6-azauridine
  • 4h)-dione,2-(2’,3’,5’-triacetyl-beta-d-ribofuranosyl)-as-triazine-5-(2h
  • cb304
CAS:
2169-64-4
MF:
C14H17N3O9
MW:
371.3
EINECS:
218-515-6
Mol File:
2169-64-4.mol
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6-AZAURIDINE 2',3',5'-TRIACETATE Chemical Properties

Melting point:
99-101 °C(lit.)
Boiling point:
501.01°C (rough estimate)
Density 
1.3535 (rough estimate)
refractive index 
1.5700 (estimate)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
2
RTECS 
XY8577000

MSDS

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6-AZAURIDINE 2',3',5'-TRIACETATE Usage And Synthesis

Chemical Properties

white to off-white powder or crystals

Uses

Antipsoriatic.

Definition

ChEBI: A N-glycosyl-1,2,4-triazine that is 6-azauridine acetylated at positions 2', 3' and 5' on the sugar ring. It is a prodrug for 6-azauridine and is used for treatment of psoriasis.

brand name

Triazure (Parke-Davis);Cb 304;Ribo-azauracil.

World Health Organization (WHO)

Azaribine, an antineoplastic agent, was introduced in 1975 for the treatment of severe, recalcitrant, disabling arthritis. Following reports of thromboembolic and thrombotic reactions, the drug was withdrawn in the USA in 1976. The causal relationship between azaribine and these events has been questioned and the drug remains available in the USA for investigational purposes.

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