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(5-Chloropyridin-3-yl)boronic acid

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(5-Chloropyridin-3-yl)boronic acid Basic information

Product Name:
(5-Chloropyridin-3-yl)boronic acid
Synonyms:
  • 5-CHLORO-3-PYRIDINEBORONIC ACID
  • 5-CHLORO-3-PYRIDINYL BORONIC ACID
  • 5-CHLOROPYRIDIN-3-YLBORONIC ACID
  • 5-CHLOROPYRIDINE-3-BORONIC ACID
  • 5-Chloropyridne-3-boronic acid
  • 3-Chloropyridine-5-boronic acid
  • (3-Chloro-5-pyridyl)boronic acid
  • 5-chloropyridin-3-yl-3-boronic acid
CAS:
872041-85-5
MF:
C5H5BClNO2
MW:
157.36
EINECS:
677-212-0
Product Categories:
  • Heteroaryl Boronic Acids
  • Boronic Acids
  • Organoborons
  • Boronic Acids and Derivatives
  • Chemical Synthesis
  • Organometallic Reagents
  • blocks
  • BoronicAcids
  • Pyridines
  • Pyridine
Mol File:
872041-85-5.mol
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(5-Chloropyridin-3-yl)boronic acid Chemical Properties

Melting point:
255-260℃
Boiling point:
335.3±52.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
form 
powder
pka
5.91±0.10(Predicted)
color 
White
InChIKey
NJXYBTMCTZAUEE-UHFFFAOYSA-N
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2933399990
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(5-Chloropyridin-3-yl)boronic acid Usage And Synthesis

Uses

5-Chloro-3-pyridineboronic acid can be used as an intermediate:

  • In the preparation of positron emission tomography (PET) radioligand [11C]MK-1064, which is applicable in the orexin-2 receptor imaging.
  • In the synthesis of orexin 2 receptor antagonist (2-SORA) MK-1064.
  • In the preparation of pyridyl-cycloalkyl derived microsomal prostaglandin E synthase-1 inhibitors.
  • In the synthesis of ATAD2 bromodomain inhibitors.

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