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Nicotinic Acid Riboside

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Nicotinic Acid Riboside Basic information

Product Name:
Nicotinic Acid Riboside
Synonyms:
  • nicotinic acid ribonucleoside
  • 3-Carboxy-1-β-D-ribofuranosyl- pyridiniuM Hydroxide Inner Salt
  • 3-Carboxy-1-β-D-ribofuranosylpyridiniuM Inner Salt
  • Nicotinic Riboside
  • NARH - oxidized form
  • 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate
  • NICOTINIC ACID RIBOSIDE
  • beta-D-Ribosylnicotinate
CAS:
17720-18-2
MF:
C11H13NO6
MW:
255.22402
Mol File:
17720-18-2.mol
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Nicotinic Acid Riboside Chemical Properties

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Water (Slightly)
form 
Solid
color 
White to Off-White
Water Solubility 
Water : 62.5 mg/mL (244.89 mM; Need ultrasonic)
Stability:
Hygroscopic
InChI
InChI=1/C11H13NO6/c13-5-7-8(14)9(15)10(18-7)12-3-1-2-6(4-12)11(16)17/h1-4,7-10,13-15H,5H2/t7-,8?,9?,10-/s3
InChIKey
PUEDDPCUCPRQNY-KGCVILSVNA-N
SMILES
C1(O)[C@@H](CO)O[C@@H]([n+]2cccc(C([O-])=O)c2)C1O |&1:2,6,r|
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Nicotinic Acid Riboside Usage And Synthesis

Description

Nicotinic acid riboside are vitamin B3 precursors NAD+ in human diet. NAD+ has a fundamental importance for cellular biology, that derives from its essential role as a cofactor various metabolic redox reactions, as well as an obligate co-substrate for NAD+-consuming enzymes which are involved in many fundamental cellular processes including aging/longevity[1].

Chemical Properties

White Solid

Uses

An effective agent for increasing nicotinamide adenine dinucleotide (NAD) concentrations in mammalian cells.

Definition

ChEBI: D-ribosylnicotinate is conjugate base of D-ribosylnicotinic acid. It has a role as a human metabolite. It is a conjugate base of a D-ribosylnicotinic acid.

References

[1] ORLANDIIVAN; VaiMarina; AlberghinaLilia. Nicotinamide, Nicotinamide Riboside and Nicotinic Acid-Emerging Roles in Replicative and Chronological Aging in Yeast.[J]. Biomolecules, 2020, 10 4. DOI:10.3390/biom10040604.

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