SDZ 280 446
SDZ 280 446 Basic information
- Product Name:
- SDZ 280 446
- Synonyms:
-
- SDZ 280 446
- Cyclo[N-methyl-L-α-aspartyl-N-methyl-L-isoleucyl-N-methyl-L-isoleucylglycyl-N-methyl-L-valyl-O-methyl-L-tyrosyl-(2S)-2-hydroxypropanoyl-(2S)-2-piperidinecarbonyl-N-methyl-L-valyl-L-valyl], 1,1-dimethylethyl ester
- 446
- Sdz 280
- CAS:
- 129893-84-1
- MF:
- C61H99N9O14
- MW:
- 1182.49
- Mol File:
- 129893-84-1.mol
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SDZ 280 446 Chemical Properties
- Melting point:
- 146-148 °C
- Boiling point:
- 1262.0±65.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- pka
- 12.73±0.70(Predicted)
- Sequence
- cyclo-[Pec-MeVal-Val-(-O-t.Bu-MeAsp)-Melle-Melle-Gly7-MeVal-(O-MeTyr)-Hpa
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SDZ 280 446 Usage And Synthesis
Uses
SDZ 280-446 is an orally active semisynthetic cyclic peptide lactone. SDZ 280-446 can be used in anticancer research[1].
References
[1] Loor F, et al. SDZ 280-446, a novel semi-synthetic cyclopeptolide: in vitro and in vivo circumvention of the P-glycoprotein-mediated tumour cell multidrug resistance. Br J Cancer. 1992 Jan;65(1):11-8. DOI:10.1038/bjc.1992.3
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SDZ 280 446(129893-84-1)Related Product Information
- Ethyl N-acetyl-L-tyrosinate hydrate
- Pipecolamide
- AC-TYR-OME H2O
- AC-TYR(ME)-OH
- DIMETHYL-PIPERIDIN-2-YLMETHYL-AMINE
- (S)-2-Amino-3-(4-methoxyphenyl)propionicacidethylester
- AC-TYR(ME)-OME
- ETHYL[(1-METHYLPIPERIDIN-2-YL)METHYL]AMINE
- 2-OXO-2-PIPERIDIN-1-YLETHANOL
- SDZ 280 446
- N-methylpiperidine-2-carboxamide
- 2-Piperidinecarboxamide,N,N-dimethyl-(9CI)
- AC-2-METHOXY-PHE-OET
- N-ethylpiperidine-2-carboxamide
- N-[(1-PROPYL-2-PIPERIDINYL)METHYL]-1-PROPANAMINE
- (1-ETHYL-2-PIPERIDINYL)-N-METHYLMETHANAMINE
- Piperidine,1-(ethoxyacetyl)-
- H-D-ALA-BETA-ALA-OH