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methyllinderone

Basic information Safety Supplier Related

methyllinderone Basic information

Product Name:
methyllinderone
Synonyms:
  • methyllinderone
  • Tridec-5-en-3-one
  • 4-Cyclopentene-1,3-dione, 4,5-dimethoxy-2-[(2E)-1-methoxy-3-phenyl-2-propen-1-ylidene]-
CAS:
3984-73-4
MF:
C17H16O5
MW:
300.31
EINECS:
200-258-5
Product Categories:
  • Chalcones
Mol File:
3984-73-4.mol
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methyllinderone Chemical Properties

Melting point:
83-85 °C
Boiling point:
570.1±50.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
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methyllinderone Usage And Synthesis

Uses

Methyllinderone is an inhibitor of AP-1/STAT/ERK. Methyllinderone has anti-inflammatory effect. Methyllinderone reduce the invasion and migration rate of TPA-stimulated MCF-7 cells. Methyllinderone can be used in study breast cancer metastasis[1].

target

Antifection

References

[1] Yoon JH, et al. Methyl Linderone Suppresses TPA-Stimulated IL-8 and MMP-9 Expression Via the ERK/STAT3 Pathway in MCF-7 Breast Cancer Cells. J Microbiol Biotechnol. 2020 Mar 28;30(3):325-332. DOI:10.4014/jmb.1911.11068

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