ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > L 683519
L 683519
L 683519 Basic information
- Product Name:
- L 683519
- Synonyms:
-
- L 683519
- Desmethyl Tacrolimus
- Tacrolimus Impurity 23（Desmethyl Tacrolimus）
- Tacrolimus 13 DMT
- Demethyltacrolimus
- Tacrolimus Impurity 14
- 16,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,15,19-trihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14-methoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,...
- 13-Desmethyl FK 506
- CAS:
- 132172-14-6
- MF:
- C43H67NO12
- MW:
- 790
- Mol File:
- 132172-14-6.mol
More
Less
L 683519 Chemical Properties
- Boiling point:
- 888.2±75.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- pka
- 10.32±0.70(Predicted)
- InChIKey
- OKRZOXIQNKYTBL-HQZWRJTASA-N
- SMILES
- OC12C(CC(C(C(CC(CC(=CC(C(=O)CC(O)C(C)C(C(C)=CC3CCC(O)C(OC)C3)OC(=O)C3CCCCN3C(=O)C1=O)CC=C)C)C)OC)O)O2)C |c:10|
More
Less
L 683519 Usage And Synthesis
Uses
L 683519, one of the impurities of tacrolimus, is an immunosuppressant. L 683519 can inhibit the activity of FK-506 binding protein[1].
References
[1] Chen TS, et al. Microbial transformation of immunosuppressive compounds. II. Specific desmethylation of 13-methoxy group of FK 506 and FR 900520 by an unidentified Actinomycete ATCC 53828 [corrected]. J Antibiot (Tokyo). 1992 Apr;45(4):577-80. DOI:10.7164/antibiotics.45.577
L 683519Supplier
Wuxi Minglu Medicine technology Co.,Ltd. Gold
- Tel
- 0510-88726693
- 3204601684@qq.com
Guangzhou Alice Biotechnology Co., Ltd. Gold
- Tel
- 0898-31318057 13265151549
- 3080931802@qq.com
Jiangsu Watson Bio Ltd Gold
- Tel
- 0512-81863996 13773182657;
- sales@watson.bio
Shanghai Jiapu Biotechnology Co., Ltd Gold
- Tel
- 18221901645
- 18221901645@163.com
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com