ACTH (4-9)
ACTH (4-9) Basic information
- Product Name:
- ACTH (4-9)
- Synonyms:
-
- L-Tryptophan, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-
- CAS:
- 56236-83-0
- MF:
- C42H56N12O9S
- MW:
- 905.03
- Mol File:
- 56236-83-0.mol
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ACTH (4-9) Usage And Synthesis
Uses
ACTH (4-9) is an adrenocorticotropic hormone (ACTH) fragment. ACTH (4-9) is the 4-9 sequence fragment of ACTH[1][2].
in vivo
ACTH (4-9) (1 mg/kg; i.h.; pregnant females or newborn pups) suppresses related behavioral performance capability in later life[1].
| Animal Model: | Pregnant female mouse or newborn pups[1] |
| Dosage: | 1 mg/kg |
| Administration: | Subcutaneous injection |
| Result: | Inhibited learning/memory task performance m males and females mouse. |
References
[1] Honour LC, et, al. Pre- and postnatally administered ACTH, Organon 2766 and CRF facilitate or inhibit active avoidance task performance in young adult mice. Peptides. 1988 Jul-Aug;9(4):745-50. DOI:10.1016/0196-9781(88)90116-7
[2] Sekita-Krzak J, et, al. Protective effects of ACTH (4-9) in degeneration of hippocampal nerve cells caused by dexamethasone: ultrastructural studies. Ann Univ Mariae Curie Sklodowska Med. 2002;57(2):233-8. PMID:12898845
ACTH (4-9)Supplier
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Nanjing Peptide Biotech Ltd.
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