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epothilone F

Basic information Safety Supplier Related

epothilone F Basic information

Product Name:
epothilone F
Synonyms:
  • epothilone F
  • CS-1032
  • 4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12,16-pentamethyl-, (1S,3S,7S,10R,11S,12S,16R)-
  • Ixabepilone Impurity 8 (Epothilone F)
  • (1S,3S(E),7S,10R,11S,12S,16R)-7,11-dihydroxy-3-[2-(2-hydroxymethyl-thiazol-4-yl)-1-methyl-vinyl]-8,8,10,12,16-pentamethyl-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione
  • epothilone F USP/EP/BP
CAS:
208518-52-9
MF:
C27H41NO7S
MW:
523.68
Mol File:
208518-52-9.mol
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epothilone F Chemical Properties

Boiling point:
711.3±60.0 °C(Predicted)
Density 
1.179±0.06 g/cm3(Predicted)
pka
13.15±0.10(Predicted)
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epothilone F Usage And Synthesis

Uses

Epothilone F is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.

epothilone FSupplier

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