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artemisic acid

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artemisic acid Basic information

Product Name:
artemisic acid
Synonyms:
  • artemisic acid
  • Artimisinic Acid
  • 2-[[(1R)-4β,7-Dimethyl-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalen]-1α-yl]acrylic acid
  • Qing Hau acid
  • Qinghao acid
  • 1-Naphthaleneaceticacid, 1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-a-methylene-, (1R,4R,4aS,8aR)-
  • ARTEMISININIC ACID
  • 4,11(13)-AMorphadien-12-oic acid
CAS:
80286-58-4
MF:
C15H22O2
MW:
234.33
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • Miscellaneous Natural Products
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
80286-58-4.mol
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artemisic acid Chemical Properties

Melting point:
129-131℃
Boiling point:
373.6±11.0 °C(Predicted)
Density 
1.019
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
4.32±0.11(Predicted)
form 
Solid
color 
White to Pale Yellow
LogP
5.086 (est)
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artemisic acid Usage And Synthesis

Uses

Artemisic Acid is a derivative of Artemisinin (A777500), an antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.

Definition

ChEBI: A monocarboxylic acid that is prop-2-enoic acid which is substituted at position 2 by a 4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group (the 1S,4R,4aS,8aR diastereoisomer). I is a sesquiterpenoid precursor of artemisinin, obtained from sweet wormwood, Artemisia annua.

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