QUINACRINE DIHYDROCHLORIDE DIHYDRATE
QUINACRINE DIHYDROCHLORIDE DIHYDRATE Basic information
- Product Name:
- QUINACRINE DIHYDROCHLORIDE DIHYDRATE
- Synonyms:
-
- 2-methoxy-6-chloro-9-diethylaminopentylaminoacridine
- 3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine
- 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxy-acridin
- 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine
- 6-chloro-9-((4-(dimethylamino)-1-methylbutyl)amino)-2-methoxyacridine
- haffkinine
- italchine
- n(4)-(6-chloro-2-methoxy-9-acridinyl)-n(1),n(1)-diethyl-4-pentanediamine
- CAS:
- 83-89-6
- MF:
- C23H30ClN3O
- MW:
- 399.96
- EINECS:
- 201-508-7
- Product Categories:
-
- ATABRINE
- Mol File:
- 83-89-6.mol
QUINACRINE DIHYDROCHLORIDE DIHYDRATE Chemical Properties
- Melting point:
- 247-250 °C
- Boiling point:
- 557.1±50.0 °C(Predicted)
- Density
- 1.0989 (rough estimate)
- refractive index
- 1.5790 (estimate)
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- pka
- 10.47±0.25(Predicted)
- color
- Bright yellow crystals
- EPA Substance Registry System
- Quinacrine (83-89-6)
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 37/39-26
- Hazardous Substances Data
- 83-89-6(Hazardous Substances Data)
- Toxicity
- mma-sat 500 mg/plate TXAPA9 52,237,80
MSDS
- Language:English Provider:ACROS
QUINACRINE DIHYDROCHLORIDE DIHYDRATE Usage And Synthesis
Uses
anthelmintic, antimalarial, intercalating agent
Uses
Quinacrine is an acridine that was used extensively from the mid-1920s to the end of World War II. It acts much like chloroquine and is reasonably effective. Because it causes the skin to turn yellow and, in high doses, causes yellow vision, the drug is no longer in use as an antimalarial.
Definition
ChEBI: A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Safety Profile
Poison by intravenous and subcutaneous routes. Moderately toxic by ingestion. Mutation data reported. Experimental reproductive effects. Has been implicated in aplas tic anemia. When heated to decomposition, it emits very toxic fumes of Cland NOx.
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