H-GLY-TYR-PRO-GLY-LYS-PHE-NH2 Chemical Properties

Boiling point:

1150.7±65.0 °C(Predicted)

Density 

1.300±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

form 

Solid

pka

9.84±0.15(Predicted)

color 

White to off-white

Water Solubility 

Water : 50 mg/mL (74.99 mM)

Sequence

Gly-Tyr-Pro-Gly-Lys-Phe-NH2

H-GLY-TYR-PRO-GLY-LYS-PHE-NH2 Usage And Synthesis

Uses

Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).

IC 50

PAR4

References

[1] Moschonas IC, et al. Molecular requirements involving the human platelet protease-activated receptor-4 mechanism of activation by peptide analogues of its tethered-ligand. Platelets. 2017 Mar 7:1-10. doi: 10.1080/09537104.2017.1282607. [Epub ahead of print] DOI:10.1080/09537104.2017.1282607
[2] Huang SC, et al. Proteinase-activated receptor-1 (PAR1) and PAR2 mediate relaxation of guinea pig internal anal sphincter. Regul Pept. 2014 Feb 10;189:46-50. DOI:10.1016/j.regpep.2014.03.001

H-GLY-TYR-PRO-GLY-LYS-PHE-NH2(245443-52-1)Related Product Information

• PAR-4 (1-6) amide (human)
• H-SER-LEU-ILE-GLY-ARG-LEU-NH2
• COAGULATION FACTOR II RECEPTOR-LIKE 2 (1-6) AMIDE (HUMAN)
• COAGULATION FACTOR II RECEPTOR-LIKE 2 (1-6) AMIDE (MOUSE)
• (PHE1,SER2,TYR6)-PAR-1 (1-6) AMIDE (HUMAN)
• H-SER-LEU-ILE-GLY-ARG-LEU-OH
• H-GLY-TYR-PRO-GLY-GLN-VAL-OH
• VKGILS-NH2
• H-ALA-TYR-PRO-GLY-LYS-PHE-NH2
• ALA-TYR-PRO-GLY-LYS-PHE-NH2 TRIFLUOROACETATE SALT
• H-GLY-TYR-PRO-GLY-LYS-PHE-NH2
• PROTEASE
• PROTEASE