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Isofraxidin

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Isofraxidin Basic information

Product Name:
Isofraxidin
Synonyms:
  • 7-hydroxy-6,8-dimethoxy-2h-1-benzopyran-2-on
  • 7-hydroxy-6,8-dimethoxy-2h-1-benzopyran-2-one
  • 7-hydroxy-6,8-dimethoxy-coumari
  • phytodolor
  • ISOFRAXIDIN
  • ISOFRAXIDINE
  • AKOS 243-93
  • 6,8-DIMETHOXY-7-HYDROXYCOUMARIN
CAS:
486-21-5
MF:
C11H10O5
MW:
222.19
Product Categories:
  • Coumarins
Mol File:
486-21-5.mol
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Isofraxidin Chemical Properties

Melting point:
145～147℃
Boiling point:
452.1±45.0 °C(Predicted)
Density 
1.358±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 250 mg/mL (1125.16 mM)
pka
7.92±0.20(Predicted)
form 
Solid
color 
Yellow to brown
BRN 
202652
InChI
InChI=1S/C11H10O5/c1-14-7-5-6-3-4-8(12)16-10(6)11(15-2)9(7)13/h3-5,13H,1-2H3
InChIKey
HOEVRHHMDJKUMZ-UHFFFAOYSA-N
SMILES
C1(=O)OC2=C(OC)C(O)=C(OC)C=C2C=C1
CAS DataBase Reference
486-21-5(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29322090
Storage Class
11 - Combustible Solids
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Isofraxidin Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in boiling water, insoluble in cold water, soluble in methanol, ethanol, sodium hydroxide solution, from the swollen knotty wind, prickly five plus bark, grass coral whole plant.

Uses

Isofraxidin is used as an anti-inflammatory compound. Inhibits pro-inflammatory cytokines.

Definition

ChEBI: Isofraxidin is a hydroxycoumarin.

IC 50

COX-2; TLR4; MMP-7

IsofraxidinSupplier

Weifang Clarite Pharmaceutical Technology Co., Ltd Gold
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Shandong Debek Bioengineering Co. LTD Gold
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13854830608; 13854830608
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13854830608@163.com
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18163336578
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Chembest Research Laboratories Limited
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Shandong Xiya Chemical Co., Ltd
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13355009207 13355009207
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3007715519@qq.com
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