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plantamajoside

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plantamajoside Basic information

Product Name:
plantamajoside
Synonyms:
  • plantamajoside
  • b-D-Glucopyranoside,2-(3,4-dihydroxyphenyl)ethyl 3-O-b-D-glucopyranosyl-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
  • 2-(3,4-Dihydroxyphenyl)ethyl 4-O-(3,4-dihydroxycinnamoyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranoside
  • Plantamoside
  • 2-(3,4-Dihydroxyphenyl)ethyl 3-O-beta-D-glucopyranosyl-beta-D-glucopyranoside 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
  • Purpureaside A
  • (E)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((3,4,5-trihydroxy-6-(hydroxymet
  • dihoside A
CAS:
104777-68-6
MF:
C29H36O16
MW:
640.59
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
104777-68-6.mol
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plantamajoside Chemical Properties

Boiling point:
953.0±65.0 °C(Predicted)
Density 
1.66
storage temp. 
2-8°C
solubility 
Soluble in methanol and water
form 
powder
pka
9.31±0.10(Predicted)
color 
White
InChIKey
KFEFLPDKISUVNR-ILWPCWSYNA-N
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Safety Information

Safety Statements 
24/25
HS Code 
29389090
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plantamajoside Usage And Synthesis

Chemical Properties

White crystalline powder, easily soluble in methanol, derived from plantain.

Uses

food and beverages

Definition

ChEBI: Plantamajoside is a hydroxycinnamic acid.

in vivo

Plantamajoside (20-80 mg/kg) promotes the recovery of neurological function and protects the tissue structure of the spinal cord after ASCI in a rat model of acute spinal cord injury[15].
Plantamajoside (25-100 mg/kg, i.p., 24 h) alleviates acute sepsis-induced organ dysfunction through inhibiting the TRAF6/NF-κB axis in mice[16].
Plantamajoside (10-40 mg/kg, p.o., 4 weeks) has protective activities against Cd-induced renal injury in rats[17].
Plantamajoside (25-100 mg/kg, i.p., three times at 6, 12, 18 h) ameliorates lipopolysaccharide-induced acute lung injury via suppressing NF-κB and MAPK activation in mice[18].
Plantamajoside (20-80 mg/kg, i.p., once a day for 4 weeks) modulates immune dysregulation and hepatic lipid metabolism in rats with nonalcoholic fatty liver disease via AMPK/Nrf2 elevation[19].

Animal Model:Acute sepsis C57BL/6 male mice model by caecal ligation and perforation (CLP)[16]
Dosage:25, 50, 100 mg/kg
Administration:Intraperitoneal injection (i.p.), 24 h
Result:Extended survival in CLP model.
Improved acute sepsis-triggered organ damage.
Alleviated acute sepsis-triggered apoptosis.
Relieved acute sepsis-triggered inflammatory response.
Improved acute sepsis-triggered organ damage via mediating the TRAF6/NF-κB pathway.
Improved acute sepsis-triggered apoptosis and inflammation via regulating the TRAF6/NF-κB pathway.

plantamajosideSupplier

Chengdu Herbpurify Co.Ltd. Gold
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Shenzhen Sungening Bio-Tech Co., Ltd
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+86-0755-89668383
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Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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sales@meilune.com
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