5-N-HEPTADECYLRESORCINOL
5-N-HEPTADECYLRESORCINOL Basic information
- Product Name:
- 5-N-HEPTADECYLRESORCINOL
- Synonyms:
-
- 5-N-HEPTADECYLRESORCINOL
- 5-Heptadecylbenzene-1,3-diol
- 5-Heptadecyl-1,3-benzenediol
- 5-Heptadecyl-1,3-dihydroxybenzene
- 1,3-Benzenediol, 5-heptadecyl-
- 5-Octadecylresorcinol
- 1,3-Dihydroxy-5-heptadecylbenzene (C17:0)
- CAS:
- 41442-57-3
- MF:
- C23H40O2
- MW:
- 348.56
- Mol File:
- 41442-57-3.mol
5-N-HEPTADECYLRESORCINOL Chemical Properties
- Melting point:
- 91-93 °C
- Boiling point:
- 478.0±15.0 °C(Predicted)
- Density
- 0.950±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 9.55±0.10(Predicted)
- form
- Solid
- color
- Off-white to light yellow
- BRN
- 2287460
5-N-HEPTADECYLRESORCINOL Usage And Synthesis
Uses
5-Heptadecylresorcinol may be used as an analytical reference standard for the quantification of the analyte in mango peels, rye grains and agricultural products using different chromatography techniques.
Definition
ChEBI: 5-heptadecylresorcinol is a 5-alkylresorcinol that is resorcinol which is substituted by a heptadecyl group at position 5. It is found in wheat bran. It has a role as an antineoplastic agent and a plant metabolite.
General Description
5-Heptadecylresorcinol belongs to the group of alk(en)ylresorcinols (ARs), exhibiting pharmacological properties such as anti-inflammatory, anti-carcinogenic and anti-microbial bioactivities. It is most commonly found in cereals such as barley, spelt, wheat, rye, ginkgo, mango peels, pulp, peas, etc.
in vivo
5-Heptadecylresorcinol (30 mg/kg, 150 mg/kg; po daily for 16 weeks) improves the lipid metabolism in HFD-fed ApoE?/? mice[1].
5-Heptadecylresorcinol (30 mg/kg, 150 mg/kg; po daily for 16 weeks) increases the body weight of mouse, and alleviates adipose tissue macrophage infiltration and mitochondrial dysfunction[2].
| Animal Model: | C57BL/6J mice[1][2] |
| Dosage: | 30 mg/kg, 150 mg/kg |
| Administration: | PO; daily for 16 weeks |
| Result: | Lowered serum total cholesterol, triglyceride, VLDL-C, and LDL-C levels[1]. Reduced adipose tissue macrophage infiltration from high-fat diet induced obese C57BL/6J mice[2]. |
IC 50
SIRT3
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