N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Chemical Properties

Melting point:

222-224°C

Boiling point:

581.3±50.0 °C(Predicted)

Density 

1.691±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO (Slightly), Methanol (Slightly, Heated)

pka

5.04±0.50(Predicted)

form 

Solid

color 

Yellow to Dark Yellow

Water Solubility 

Slightly soluble in water.

Sensitive 

Light Sensitive

CAS DataBase Reference

231278-20-9(CAS DataBase Reference)

Safety Information

HS Code 

2933.59.8000

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Usage And Synthesis

Description

N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-quinazolin-4-amine is a quinazoline derivative that has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.

Chemical Properties

Yellow Solid

Uses

Lapatinib intermediate

Uses

4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline is used as an organic chemical synthesis intermediate.

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine(231278-20-9)Related Product Information

• Diphenyldiethoxysilane
• 4-Methoxybenzylchloride
• Sulfaquinoxaline
• Bis(2-ethylhexyl)amine
• Quinazoline
• Diphenyldimethoxysilane
• Triallylamine
• Triethanolamine
• Quinoxaline
• Diphenyl ether
• Triethylamine
• PHENYL VALERATE
• 4-Methoxyphenylacetone
• 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone
• PHENYL RESIN
• 3-Chloro-4-(3-fluorobenzyloxy)aniline
• Lapatinib
• Phenylacetic acid