α-Amyrenone
α-Amyrenone Basic information
- Product Name:
- α-Amyrenone
- Synonyms:
-
- α-Amyrenone
- 5α-Olean-13(18)-en-3-one
- Olean-13(18)-en-3-one
- 13(18)-Oleanen-3-one
- δ-Amyrenane
- (6aR,6bS,8aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-2,4a,5,6,7,8,9,10,12,13,14,14a-dodecahydro-1H-picen-3-one
- Delta-Amyrone
- δ-Amyrenone
- CAS:
- 20248-08-2
- MF:
- C30H48O
- MW:
- 424.7
- Mol File:
- 20248-08-2.mol
More
Less
α-Amyrenone Chemical Properties
- Melting point:
- 198-201 °C
- Boiling point:
- 488.8±44.0 °C(Predicted)
- Density
- 1.01±0.1 g/cm3(Predicted)
- form
- Solid
- color
- White to off-white
- InChIKey
- KPUDOJPVQQJLGI-CKARLABJSA-N
- SMILES
- C1(=O)[C@@]([C@]2([C@](C)(CC1)[C@]1([H])[C@@]([C@]3(C(CC1)=C1[C@@](CC[C@](C1)(C)C)(C)CC3)C)(C)CC2)[H])(C)C
More
Less
α-Amyrenone Usage And Synthesis
Uses
δ-Amyrenone (Delta-Amyrone) is a pentacyclic triterpene compound from S. lineare, with anti-inflammatory effects[1].
in vivo
δ-Amyrone (4 mg/kg and 8 mg/kg; i.p.) inhibits lipopolysaccharide-induced inflammatory cytokines and protects against endotoxic shock in mice[1].
References
[1] Niu X, et al.δ-Amyrone, a specific inhibitor of cyclooxygenase-2, exhibits anti-inflammatory effects in vitro and in vivo of mice. Int Immunopharmacol. 2014 Jul;21(1):112-8. DOI:10.1016/j.intimp.2014.04.019
[2] Niu X, et al.δ-Amyrone inhibits lipopolysaccharide-induced inflammatory cytokines and protects against endotoxic shock in mice. Chem Biol Interact. 2015 Oct 5;240:354-61. DOI:10.1016/j.cbi.2015.07.007
α-AmyrenoneSupplier
Huzhou ZhanShu Biotechnology Co.,Ltd Gold
- Tel
- 0572-8889530 18167260939
- zsubio@163.com
Sichuan Kulinan Technology Co., Ltd
- Tel
- 400-1166-196 18981987031
- cdhxsj@163.com
BioBioPha Co., Ltd.
- Tel
- 0871-65217109 13211707573;
- y.liu@mail.biobiopha.com
S.Z. PhyStandard Bio-Tech. Co., Ltd.
- Tel
- 0755-83725681-603
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com