Basic information Safety Supplier Related

2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE

Basic information Safety Supplier Related

2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE Basic information

Product Name:
2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE
Synonyms:
  • 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE
  • Nintedanib impurity 3/2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide
  • 2-Chloro-N-methyl-4'-nitroacetanilide
  • Intedanib Impurity 11
  • Nintedanib intermediate
  • Nintedanib-004
  • Acetamide, 2-chloro-N-methyl-N-(4-nitrophenyl)-
  • Ethanesulfonic acid Nidanib impurity 27
CAS:
2653-16-9
MF:
C9H9ClN2O3
MW:
228.63
Product Categories:
  • Intermediate of BIBF-1120 and PKI587
  • Nintedanib
Mol File:
2653-16-9.mol
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2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE Chemical Properties

Melting point:
109.5-110 °C
Boiling point:
374.9±27.0 °C(Predicted)
Density 
1.391±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
form 
Solid
pka
-4.02±0.50(Predicted)
color 
Pale Yellow to Yellow
InChI
InChI=1S/C9H9ClN2O3/c1-11(9(13)6-10)7-2-4-8(5-3-7)12(14)15/h2-5H,6H2,1H3
InChIKey
JAWLWNKATJAODJ-UHFFFAOYSA-N
SMILES
C(N(C)C1=CC=C([N+]([O-])=O)C=C1)(=O)CCl
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2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE Usage And Synthesis

Uses

2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide can be used as reactant/reagent for synthetic preparation of oxindole derivatives as inhibitors of tyrosine kinase.

2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDESupplier

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