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3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID

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3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Basic information

Product Name:
3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID
Synonyms:
  • 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID
  • 3'-Amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
  • Eltrombopag Intermediate 2
  • EltroMbopag I
  • 3-(3-aMino-2-hydroxyphenyl)benzoic acid
  • [1,1'-Biphenyl]-3-carboxylic acid, 3'-aMino-2'-hydroxy-
  • 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC
  • Eltrombopag olamine Intermediate 1
CAS:
376592-93-7
MF:
C13H11NO3
MW:
229.23
EINECS:
814-404-7
Product Categories:
  • 376592-93-7
Mol File:
376592-93-7.mol
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3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Chemical Properties

Melting point:
222 °C(dec.)
Boiling point:
474.8±45.0 °C(Predicted)
Density 
1.364
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
3.99±0.10(Predicted)
color 
Pale Yellow to Light Brown
InChI
InChI=1S/C13H11NO3/c14-11-6-2-5-10(12(11)15)8-3-1-4-9(7-8)13(16)17/h1-7,15H,14H2,(H,16,17)
InChIKey
ZXLYSSHNDUXXIN-UHFFFAOYSA-N
SMILES
C1(C2=CC=CC(N)=C2O)=CC=CC(C(O)=O)=C1
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Safety Information

HS Code 
2922.50.5000
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3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Usage And Synthesis

Uses

3’-Amino-2’-Hydroxy-[1,1’]Biphenyl-3-carboxylic Acid is used in the synthesis of monoethanolamine salts. A hydrazine cleavage product from Eltrombopag (E508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia

3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACIDSupplier

Jinan XuanDe Chemical Co., Ltd. Gold
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3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID(376592-93-7)Related Product Information