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6-Bromobenzo[d]isothiazole-3-carboxylic acid

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6-Bromobenzo[d]isothiazole-3-carboxylic acid Basic information

Product Name:
6-Bromobenzo[d]isothiazole-3-carboxylic acid
Synonyms:
  • 6-bromobenzo[d]isothiazole-3-carboxylic acid
  • 6-Bromo-1,2-benzisothiazole-3-carboxylic acid
  • 6-Bromo-1,2-benzenisothiazole-carboxylic acid
  • 6-Bromobenzoisothiazole-3-carboxylic Acid
  • 6-bromo-1,2-benzothiazole-3-carboxylic acid
  • 1,2-Benzisothiazole-3-carboxylic acid, 6-bromo-
  • 6-Bromobenzodisothiazol-3-carboxylic acid
CAS:
677304-75-5
MF:
C8H4BrNO2S
MW:
258.09
Mol File:
677304-75-5.mol
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6-Bromobenzo[d]isothiazole-3-carboxylic acid Chemical Properties

Boiling point:
337.5±24.0 °C(Predicted)
Density 
1.912
storage temp. 
2-8°C
pka
4.69±0.50(Predicted)
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6-Bromobenzo[d]isothiazole-3-carboxylic acid Usage And Synthesis

Synthesis

NaOH solution (10 mL, 100 mmol) was added to a solution of 6- bromobenzo[b]thiophene-3-carboxamide (1.20 g, 4.67 mmol) in MeOH (80 mL). The mixture was heated at reflux overnight. After cooling, the mixture was acidified with 2N HCl. The resulting precipitate was filtered and dried to give 6-Bromobenzo[d]isothiazole-3-carboxylic acid (1.10 g, 91percent) as a solid.

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